ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for acid out of >500 occurrences
272943 occurrences (No.93 in the rank) during 5 years in the PubMed. [cache]
155) This study aimed to evaluate arsenic-induced apoptosis in the hepatocytes of rat and its protective efficacy with coadministration of ascorbic acid (AA) and Pleurotus florida lectin (PFL) individually.
--- ABSTRACT ---
PMID:23282998 DOI:10.1177/0748233712468026
2015 Toxicology and industrial health
* Characterization of arsenic-induced cytotoxicity in liver with stress in erythrocytes and its reversibility with Pleurotus florida lectin.
- Arsenic is one of the most hazardous substances in the environment known to cause toxicity in multiple organs. Cell adhesion, morphological alterations, cell proliferation, terminal deoxyuridine triphosphate nick-end labeling (TUNEL) and caspase-3/CPP32 fluorometric protease assay were important biomarkers to assess apoptosis in cells. This study aimed to evaluate arsenic-induced apoptosis in the hepatocytes of rat and its protective efficacy with coadministration of ascorbic acid (AA) and Pleurotus florida lectin (PFL) individually. Results of the present study also showed that arsenic caused cytotoxicity by elevating morphological alterations, TUNEL-positive nuclei, caspase-3 activity and DNA damage and reducing cell adhesion and cell proliferation in a time-dependent manner. The apoptosis in hepatocytes was reverted to normal value after coadministration of mushroom lectin in arsenic-exposed rat. The study provided significant evidence that PFL has antiapoptotic property against arsenic-induced toxicity. The beneficial effect of PFL was proportional to its duration of exposure. Retard activities of superoxide dismutase and catalase, enhanced lipid peroxidation as well as protein carbonyl in erythrocytes caused by arsenic could also be maintained toward normalcy by supplementation of AA and PFL. These antioxidative effects were exhibited in a time-dependant manner. In rat, treatment with AA and PFL prevented alteration of plasma enzyme activities caused by arsenic. The results concluded that treatment with PFL has significant role in protecting animals from arsenic-induced erythrocytic damage. This finding might be of therapeutic benefit in people suffering from chronic exposure to arsenic from natural sources, a global problem especially relevant to millions of people on the Indian subcontinent.
--- ABSTRACT END ---
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(1)29 and (20)4 treatment (39)2 (FA) (58)2 from
(2)15 *null* (21)3 (AA) (40)2 (PA) (59)2 hydrolysis
(3)11 in (22)3 (ALA) (41)2 (PLGA) (60)2 interactions
(4)10 phenethyl (23)3 (GABA) (42)2 (PLGA), (61)2 may
(5)10 phosphatase (24)3 (NEFA) (43)2 (SA) (62)2 nanoparticles
(6)9 is (25)3 changes (44)2 (SLA) (63)2 peptide
(7)8 was (26)3 decarboxylase (45)2 (TA) (64)2 proteins
(8)6 (HA) (27)3 etching (46)2 (TCA) (65)2 racemization
(9)6 reactive (28)3 levels (47)2 A (66)2 ratio
(10)5 as (29)3 metabolism (48)2 BSA (67)2 residues
(11)5 bacteria (30)3 on (49)2 Ig-superfamily (68)2 substances
(12)5 group (31)3 protein (50)2 Schiff (69)2 suppressive
(13)5 or (32)3 sequence (51)2 biosynthesis (70)2 synthetase
(14)5 synthesis (33)3 sequences (52)2 by (71)2 the
(15)5 to (34)3 status (53)2 changes, (72)2 therapy
(16)4 binding (35)3 were (54)2 composition (73)2 vitamin
(17)4 derivatives (36)2 (DHA) (55)2 contents
(18)4 for (37)2 (EDTA) (56)2 cycle
(19)4 solution (38)2 (EPA) (57)2 extract

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--- WordNet output for acid --- =>1.酸っぱい, 2.辛辣な, 3.酸, 4.《俗語》麻薬, LSD Overview of noun acid The noun acid has 2 senses (first 1 from tagged texts) 1. (4) acid -- (any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt) 2. acid, back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen -- (street name for lysergic acid diethylamide) Overview of adj acid The adj acid has 3 senses (first 1 from tagged texts) 1. (1) acerb, acerbic, acid, acrid, bitter, blistering, caustic, sulfurous, sulphurous, virulent, vitriolic -- (harsh or corrosive in tone; "an acerbic tone piercing otherwise flowery prose"; "a barrage of acid comments"; "her acrid remarks make her many enemies"; "bitter words"; "blistering criticism"; "caustic jokes about political assassination, talk-show hosts and medical ethics"; "a sulfurous denunciation"; "a vitriolic critique") 2. acidic, acid, acidulent, acidulous -- (being sour to the taste) 3. acid -- (having the characteristics of an acid; "an acid reaction") --- WordNet end ---