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return kwic search for acid out of >500 occurrences
272943 occurrences (No.93 in the rank) during 5 years in the PubMed. [no cache] 500 found

173) Tranexamic acid reduced the risk of early (aOR 0.79, 0.63-0.99; p = 0.041) but not late neurological deterioration (aOR 0.76, 0.52-1.11; p = 0.15).

--- ABSTRACT ---

PMID:32902808 DOI:10.1007/s12975-020-00845-6

2021 Translational stroke research

* Predictors and Outcomes of Neurological Deterioration in Intracerebral Hemorrhage: Results from the TICH-2 Randomized Controlled Trial.

- Neurological deterioration is common after intracerebral hemorrhage (ICH). We aimed to identify the predictors and effects of neurological deterioration and whether tranexamic acid reduced the risk of neurological deterioration. Data from the Tranexamic acid in IntraCerebral Hemorrhage-2 (TICH-2) randomized controlled trial were analyzed. Neurological deterioration was defined as an increase in National Institutes of Health Stroke Scale (NIHSS) of ≥ 4 or a decline in Glasgow Coma Scale of ≥ 2. Neurological deterioration was considered to be early if it started ≤ 48 h and late if commenced between 48 h and 7 days after onset. Logistic regression was used to identify predictors and effects of neurological deterioration and the effect of tranexamic acid on neurological deterioration. Of 2325 patients, 735 (31.7%) had neurological deterioration: 590 (80.3%) occurred early and 145 (19.7%) late. Predictors of early neurological deterioration included recruitment from the UK, previous ICH, higher admission systolic blood pressure, higher NIHSS, shorter onset-to-CT time, larger baseline hematoma, intraventricular hemorrhage, subarachnoid extension and antiplatelet therapy. Older age, male sex, higher NIHSS, previous ICH and larger baseline hematoma predicted late neurological deterioration. Neurological deterioration was independently associated with a modified Rankin Scale of > 3 (aOR 4.98, 3.70-6.70; p < 0.001). Tranexamic acid reduced the risk of early (aOR 0.79, 0.63-0.99; p = 0.041) but not late neurological deterioration (aOR 0.76, 0.52-1.11; p = 0.15). Larger hematoma size, intraventricular and subarachnoid extension increased the risk of neurological deterioration. Neurological deterioration increased the risk of death and dependency at day 90. Tranexamic acid reduced the risk of early neurological deterioration and warrants further investigation in ICH. URL: https://www.isrctn.com Unique identifier: ISRCTN93732214.

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(1)26 and	(19)3 (GABA)	(37)2 (AMPA)	(55)2 glycoprotein
(2)13 metabolism	(20)3 (HA)	(38)2 (ASA)	(56)2 group
(3)11 null	(21)3 A,	(39)2 (BA)	(57)2 have
(4)10 oxidation	(22)3 Gels	(40)2 (FA)	(58)2 injury
(5)9 receptor	(23)3 amide	(41)2 (GABA)ergic	(59)2 ion
(6)8 in	(24)3 amplification	(42)2 (HAuCl4)	(60)2 is
(7)7 residues	(25)3 ceramidase	(43)2 (IAA),	(61)2 layer
(8)6 cycle	(26)3 delivery	(44)2 (OCA),	(62)2 mutations
(9)6 transporter	(27)3 moiety	(45)2 (TCA)	(63)2 positions
(10)6 was	(28)3 protein	(46)2 Amide	(64)2 quantification
(11)5 or	(29)3 protein,	(47)2 alone	(65)2 regulation
(12)5 sequence	(30)3 receptors	(48)2 binding	(66)2 substitution
(13)4 biosynthesis	(31)3 reduced	(49)2 biosensor	(67)2 synthesis
(14)4 composition	(32)3 regurgitation	(50)2 burns	(68)2 the
(15)4 levels	(33)3 sequences	(51)2 cargo	(69)2 transporter,
(16)4 metabolism,	(34)3 transport	(52)2 changes	(70)2 variants
(17)4 structures	(35)3 transporters	(53)2 diethylamide	(71)2 wet
(18)4 substitutions	(36)3 were	(54)2 from

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--- WordNet output for acid --- =>1.酸っぱい, 2.辛辣な, 3.酸, 4.《俗語》麻薬, LSD Overview of noun acid The noun acid has 2 senses (first 1 from tagged texts) 1. (4) acid -- (any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt) 2. acid, back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen -- (street name for lysergic acid diethylamide) Overview of adj acid The adj acid has 3 senses (first 1 from tagged texts) 1. (1) acerb, acerbic, acid, acrid, bitter, blistering, caustic, sulfurous, sulphurous, virulent, vitriolic -- (harsh or corrosive in tone; "an acerbic tone piercing otherwise flowery prose"; "a barrage of acid comments"; "her acrid remarks make her many enemies"; "bitter words"; "blistering criticism"; "caustic jokes about political assassination, talk-show hosts and medical ethics"; "a sulfurous denunciation"; "a vitriolic critique") 2. acidic, acid, acidulent, acidulous -- (being sour to the taste) 3. acid -- (having the characteristics of an acid; "an acid reaction") --- WordNet end ---