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- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for acid out of >500 occurrences
272943 occurrences (No.93 in the rank) during 5 years in the PubMed. [no cache] 500 found
222) NG2 cells, a main pool of glial progenitors, express γ-aminobutyric acid A (GABA(A)) receptors (GABA(A)Rs), the functional and molecular properties of which are largely unknown.
--- ABSTRACT ---
PMID:24217990 DOI:10.1093/cercor/bht309
2015 Cerebral cortex (New York, N.Y. : 1991)
* Postnatal down-regulation of the GABAA receptor γ2 subunit in neocortical NG2 cells accompanies synaptic-to-extrasynaptic switch in the GABAergic transmission mode.
- NG2 cells, a main pool of glial progenitors, express γ-aminobutyric acid A (GABA(A)) receptors (GABA(A)Rs), the functional and molecular properties of which are largely unknown. We recently reported that transmission between GABAergic interneurons and NG2 cells drastically changes during development of the somatosensory cortex, switching from synaptic to extrasynaptic communication. Since synaptic and extrasynaptic GABA(A)Rs of neurons differ in their subunit composition, we hypothesize that GABA(A)Rs of NG2 cells undergo molecular changes during cortical development accompanying the switch of transmission modes. Single-cell RT-PCR and the effects of zolpidem and α5IA on evoked GABAergic currents reveal the predominance of functional α1- and α5-containing GABA(A)Rs at interneuron-NG2 cell synapses in the second postnatal week, while the α5 expression declines later in development when responses are exclusively extrasynaptic. Importantly, pharmacological and molecular analyses demonstrate that γ2, a subunit contributing to the clustering of GABA(A)Rs at postsynaptic sites in neurons, is down-regulated in NG2 cells in a cell type-specific manner in concomitance with the decline of synaptic activity and the switch of transmission mode. In keeping with the synaptic nature of γ2 in neurons, the down-regulation of this subunit is an important molecular hallmark of the change of transmission modes between interneurons and NG2 cells during development.
--- ABSTRACT END ---
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[frequency of next (right) word to acid]
(1)29 and (20)4 treatment (39)2 (FA) (58)2 from
(2)15 *null* (21)3 (AA) (40)2 (PA) (59)2 hydrolysis
(3)11 in (22)3 (ALA) (41)2 (PLGA) (60)2 interactions
(4)10 phenethyl (23)3 (GABA) (42)2 (PLGA), (61)2 may
(5)10 phosphatase (24)3 (NEFA) (43)2 (SA) (62)2 nanoparticles
(6)9 is (25)3 changes (44)2 (SLA) (63)2 peptide
(7)8 was (26)3 decarboxylase (45)2 (TA) (64)2 proteins
(8)6 (HA) (27)3 etching (46)2 (TCA) (65)2 racemization
(9)6 reactive (28)3 levels (47)2 A (66)2 ratio
(10)5 as (29)3 metabolism (48)2 BSA (67)2 residues
(11)5 bacteria (30)3 on (49)2 Ig-superfamily (68)2 substances
(12)5 group (31)3 protein (50)2 Schiff (69)2 suppressive
(13)5 or (32)3 sequence (51)2 biosynthesis (70)2 synthetase
(14)5 synthesis (33)3 sequences (52)2 by (71)2 the
(15)5 to (34)3 status (53)2 changes, (72)2 therapy
(16)4 binding (35)3 were (54)2 composition (73)2 vitamin
(17)4 derivatives (36)2 (DHA) (55)2 contents
(18)4 for (37)2 (EDTA) (56)2 cycle
(19)4 solution (38)2 (EPA) (57)2 extract

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--- WordNet output for acid --- =>1.酸っぱい, 2.辛辣な, 3.酸, 4.《俗語》麻薬, LSD Overview of noun acid The noun acid has 2 senses (first 1 from tagged texts) 1. (4) acid -- (any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt) 2. acid, back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen -- (street name for lysergic acid diethylamide) Overview of adj acid The adj acid has 3 senses (first 1 from tagged texts) 1. (1) acerb, acerbic, acid, acrid, bitter, blistering, caustic, sulfurous, sulphurous, virulent, vitriolic -- (harsh or corrosive in tone; "an acerbic tone piercing otherwise flowery prose"; "a barrage of acid comments"; "her acrid remarks make her many enemies"; "bitter words"; "blistering criticism"; "caustic jokes about political assassination, talk-show hosts and medical ethics"; "a sulfurous denunciation"; "a vitriolic critique") 2. acidic, acid, acidulent, acidulous -- (being sour to the taste) 3. acid -- (having the characteristics of an acid; "an acid reaction") --- WordNet end ---