ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for acid out of >500 occurrences
272943 occurrences (No.93 in the rank) during 5 years in the PubMed. [no cache] 500 found
268) In this chapter we focus on the enzyme catalyzing the activation of sialic acid, the CMP-sialic acid synthetase (CMAS), and compare the enzymatic properties of CMASs isolated from different species.
--- ABSTRACT ---
PMID:24141690 DOI:10.1007/128_2013_477
2015 Topics in current chemistry
* CMP-Sialic Acid Synthetase: The Point of Constriction in the Sialylation Pathway.
- Sialoglycoconjugates form the outermost layer of animal cells and play a crucial role in cellular communication processes. An essential step in the biosynthesis of sialylated glycoconjugates is the activation of sialic acid to the monophosphate diester CMP-sialic acid. Only the activated sugar is transported into the Golgi apparatus and serves as a substrate for the linkage-specific sialyltransferases. Interference with sugar activation abolishes sialylation and is embryonic lethal in mammals. In this chapter we focus on the enzyme catalyzing the activation of sialic acid, the CMP-sialic acid synthetase (CMAS), and compare the enzymatic properties of CMASs isolated from different species. Information concerning the reaction mechanism and active site architecture is included. Moreover, the unusual nuclear localization of vertebrate CMASs as well as the biotechnological application of bacterial CMAS enzymes is addressed.
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(1)29 and (20)4 treatment (39)2 (FA) (58)2 from
(2)15 *null* (21)3 (AA) (40)2 (PA) (59)2 hydrolysis
(3)11 in (22)3 (ALA) (41)2 (PLGA) (60)2 interactions
(4)10 phenethyl (23)3 (GABA) (42)2 (PLGA), (61)2 may
(5)10 phosphatase (24)3 (NEFA) (43)2 (SA) (62)2 nanoparticles
(6)9 is (25)3 changes (44)2 (SLA) (63)2 peptide
(7)8 was (26)3 decarboxylase (45)2 (TA) (64)2 proteins
(8)6 (HA) (27)3 etching (46)2 (TCA) (65)2 racemization
(9)6 reactive (28)3 levels (47)2 A (66)2 ratio
(10)5 as (29)3 metabolism (48)2 BSA (67)2 residues
(11)5 bacteria (30)3 on (49)2 Ig-superfamily (68)2 substances
(12)5 group (31)3 protein (50)2 Schiff (69)2 suppressive
(13)5 or (32)3 sequence (51)2 biosynthesis (70)2 synthetase
(14)5 synthesis (33)3 sequences (52)2 by (71)2 the
(15)5 to (34)3 status (53)2 changes, (72)2 therapy
(16)4 binding (35)3 were (54)2 composition (73)2 vitamin
(17)4 derivatives (36)2 (DHA) (55)2 contents
(18)4 for (37)2 (EDTA) (56)2 cycle
(19)4 solution (38)2 (EPA) (57)2 extract

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--- WordNet output for acid --- =>1.酸っぱい, 2.辛辣な, 3.酸, 4.《俗語》麻薬, LSD Overview of noun acid The noun acid has 2 senses (first 1 from tagged texts) 1. (4) acid -- (any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt) 2. acid, back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen -- (street name for lysergic acid diethylamide) Overview of adj acid The adj acid has 3 senses (first 1 from tagged texts) 1. (1) acerb, acerbic, acid, acrid, bitter, blistering, caustic, sulfurous, sulphurous, virulent, vitriolic -- (harsh or corrosive in tone; "an acerbic tone piercing otherwise flowery prose"; "a barrage of acid comments"; "her acrid remarks make her many enemies"; "bitter words"; "blistering criticism"; "caustic jokes about political assassination, talk-show hosts and medical ethics"; "a sulfurous denunciation"; "a vitriolic critique") 2. acidic, acid, acidulent, acidulous -- (being sour to the taste) 3. acid -- (having the characteristics of an acid; "an acid reaction") --- WordNet end ---