* Fatty acid effect on sucrose-induced enamel demineralization and cariogenicity of an experimental biofilm-caries model.
- Based on scarce evidence, fatty acids have been described as anticariogenic. The aim was to evaluate the effect of different types of fatty acids on enamel demineralization and on the cariogenic properties of Streptococcus mutans biofilms on a biofilm/caries model. Mature biofilms of S. mutans UA159 growing on bovine enamel slabs were exposed to 10% sucrose for 5 min, 3 times per day followed by exposure to a panel of free fatty acids, including monounsaturated (oleic), polyunsaturated (linoleic) and saturated (stearic) fatty acids, in concentrations of 0.1, 1 and 10 mM for five additional minutes. Enamel demineralization was determined before and after the experiments by microhardness. Slabs were retrieved to analyze biofilm biomass, viable bacterial counts and polysaccharide production. Biofilms exposed to sucrose, followed by oleic and linoleic acids, showed less demineralization than sucrose alone (p < 0.05). Biomass, S. mutans colonies and insoluble extracellular polysaccharide production were reduced from the biofilms treated with oleic and linoleic fatty acids (p < 0.05). No differences with the positive control were observed with the saturated stearic acid. Poly and monounsaturated fatty acids presented to S. mutans biofilms after a cariogenic challenge appear to reduce demineralization on enamel and to interfere with cariogenicity of S. mutans biofilms.
=>1.酸っぱい, 2.辛辣な, 3.酸, 4.《俗語》麻薬, LSD
Overview of noun acid
The noun acid has 2 senses (first 1 from tagged texts)
1. (4) acid -- (any of various water-soluble compounds having a sour taste and capable of turning
litmus red and reacting with a base to form a salt)
2. acid, back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds,
pane, superman, window pane, Zen -- (street name for lysergic acid diethylamide)
Overview of adj acid
The adj acid has 3 senses (first 1 from tagged texts)
1. (1) acerb, acerbic, acid, acrid, bitter, blistering, caustic, sulfurous, sulphurous, virulent,
vitriolic -- (harsh or corrosive in tone; "an acerbic tone piercing otherwise flowery prose"; "a
barrage of acid comments"; "her acrid remarks make her many enemies"; "bitter words"; "blistering
criticism"; "caustic jokes about political assassination, talk-show hosts and medical ethics"; "a
sulfurous denunciation"; "a vitriolic critique")
2. acidic, acid, acidulent, acidulous -- (being sour to the taste)
3. acid -- (having the characteristics of an acid; "an acid reaction")
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