ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
return
kwic search for analysis out of >500 occurrences
560012 occurrences (No.18 in the rank) during 5 years in the PubMed. [cache]
417) Recent whole genome sequencing of Leptospira species and development of in silico analysis tools have led to the identification of a large number of leptospiral virulence genes, metabolic pathways and surface protein secretion systems that represent potential new targets for the development of anti-leptospiral drug, vaccine and diagnostic strategies.
* Pathogenic, diagnostic and vaccine potential of leptospiral outer membrane proteins (OMPs).
- Pathogenic Leptospira species are important human and animal pathogen that causes leptospirosis, with more than half a million cases reported annually but little is known regarding the true incidence of leptospirosis due to the limitations in diagnosis. Proteins embedded in the outer membrane are found to be prime drug targets due to its key role as receptors for cellular communication and gatekeepers for iron and substrate transport across cell membranes. The major key issues to be addressed to overcome the disease burden of leptospirosis are: need to identify the genes that turn on in vivo; development of rapid diagnostic methods to facilitate the early diagnosis and to develop a universal vaccine. Recent whole genome sequencing of Leptospira species and development of in silico analysis tools have led to the identification of a large number of leptospiral virulence genes, metabolic pathways and surface protein secretion systems that represent potential new targets for the development of anti-leptospiral drug, vaccine and diagnostic strategies. This review surveys the different types of outer membrane proteins (OMPs) of Leptospira and combines all the novel features of OMPs reported till date and put forth some views for future research.
=>詳細な検討, 分解, 分析, 解析, 見方, 精神分析
Overview of noun analysis
The noun analysis has 6 senses (first 3 from tagged texts)
1. (45) analysis -- (an investigation of the component parts of a whole and their relations in
making up the whole)
2. (5) analysis, analytic thinking -- (the abstract separation of a whole into its constituent parts
in order to study the parts and their relations)
3. (2) analysis -- (a form of literary criticism in which the structure of a piece of writing is
analyzed)
4. analysis -- (the use of closed-class words instead of inflections: e.g., `the father of the
bride' instead of `the bride's father')
5. analysis -- (a branch of mathematics involving calculus and the theory of limits; sequences and
series and integration and differentiation)
6. psychoanalysis, analysis, depth psychology -- (a set of techniques for exploring underlying
motives and a method of treating various mental disorders; based on the theories of Sigmund Freud;
"his physician recommended psychoanalysis")
--- WordNet end ---