350) Cancer research is increasingly dependent on access to biospecimens from subjects that have been followed-up for future health outcomes. |
PMID:24239448 DOI:10.1016/j.ejca.2013.10.007 |
2015 European journal of cancer (Oxford, England : 1990) |
* A basis for translational cancer research on aetiology, pathogenesis and prognosis: Guideline for standardised and population-based linkages of biobanks to cancer registries. |
- Population-based cancer research is paramount for controlling cancer. Cancer research is increasingly dependent on access to biospecimens from subjects that have been followed-up for future health outcomes. This is achieved using longitudinal follow-up of cohorts and biobanks using cancer registry linkages. All over the world, more and more large population-based cohorts and advanced biobanking facilities are established. International standardisation and networking in the linkage of cohorts and biobanks to cancer registries is required in order to enable international cancer research and comparability of research results. An international operating procedure and standard minimum dataset for linkages of biobanks, cohorts and cancer registries is proposed. An internationally comparable provision of well characterised study bases for molecular cancer research will be an essential prerequisite for the success of translational medicine. |
(1)65 *null* | (14)6 therapy | (27)3 of | (40)2 epigenetics |
(2)48 cells | (15)6 tissues | (28)3 patients, | (41)2 growth |
(3)33 and | (16)5 cells, | (29)3 research | (42)2 initiation |
(4)32 cell | (17)5 progression | (30)3 was | (43)2 prevention |
(5)23 patients | (18)5 registries | (31)2 (GC) | (44)2 registry |
(6)15 in | (19)4 at | (32)2 biology | (45)2 study |
(7)14 is | (20)4 deaths | (33)2 but | (46)2 susceptibility |
(8)12 risk | (21)4 has | (34)2 can | (47)2 than |
(9)12 screening | (22)4 mortality | (35)2 care | (48)2 treated |
(10)12 stem | (23)3 (CRC) | (36)2 development | (49)2 treatment |
(11)9 survivors | (24)3 as | (37)2 diagnostic | (50)2 using |
(12)7 with | (25)3 cases | (38)2 drug | |
(13)6 are | (26)3 metabolism | (39)2 drugs |
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