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505522 occurrences (No.25 in the rank) during 5 years in the PubMed. [no cache] 500 found

360) This meta-analysis suggested that the ADH1C (1) allele might modestly influence the effect of alcohol on breast cancer but is not an independent risk factor for breast cancer.

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PMID:22652248 DOI:10.1177/1010539512446962

2015 Asia-Pacific journal of public health

* The alcohol dehydrogenase 1C(rs698) genotype and breast cancer: a meta-analysis.

- Published data regarding the association between alcohol dehydrogenase (ADH) 1C genotypes and breast cancer risk show conflicting results. The authors performed this meta-analysis on 1969 patients and 2244 controls from 4 (including 7 study populations) related case-control studies to estimate the association between ADH1C(rs698) genotyping information and breast cancer risk. According to the 6 eligible populations, the odds ratios (ORs) and 95% confidence intervals (CIs) for breast cancer risk for ADH1C (1-2) versus ADH1C (2-2) , ADH1C (1-1) versus ADH1C (2-2) genotype, and ADH1C (1) versus ADH1C (2) were 1.16 (0.95-1.42), 1.17 (0.95-1.44), and 1.05 (0.96-1.16), respectively. The OR (95% CI) for ADH1C (1-1) + ADH1C (1-2) versus ADH1C (2-2) from the 7 study populations was 1.14 (0.96-1.36). Meanwhile, genotypes of ADH1C (1-1) + ADH1C (1-2) increased the risk of breast cancer in drinkers (OR = 1.35; 95% CI = 1.03-1.76). This meta-analysis suggested that the ADH1C (1) allele might modestly influence the effect of alcohol on breast cancer but is not an independent risk factor for breast cancer. However, more restricted prospective studies are needed.

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(1)65 null	(14)6 therapy	(27)3 of	(40)2 epigenetics
(2)48 cells	(15)6 tissues	(28)3 patients,	(41)2 growth
(3)33 and	(16)5 cells,	(29)3 research	(42)2 initiation
(4)32 cell	(17)5 progression	(30)3 was	(43)2 prevention
(5)23 patients	(18)5 registries	(31)2 (GC)	(44)2 registry
(6)15 in	(19)4 at	(32)2 biology	(45)2 study
(7)14 is	(20)4 deaths	(33)2 but	(46)2 susceptibility
(8)12 risk	(21)4 has	(34)2 can	(47)2 than
(9)12 screening	(22)4 mortality	(35)2 care	(48)2 treated
(10)12 stem	(23)3 (CRC)	(36)2 development	(49)2 treatment
(11)9 survivors	(24)3 as	(37)2 diagnostic	(50)2 using
(12)7 with	(25)3 cases	(38)2 drug
(13)6 are	(26)3 metabolism	(39)2 drugs

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--- WordNet output for cancer --- =>【病名】がん, 悪性腫瘍(しゅよう), がん腫, 社会悪, 癌 Overview of noun cancer The noun cancer has 5 senses (first 1 from tagged texts) 1. (15) cancer, malignant neoplastic disease -- (any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream) 2. Cancer, Crab -- ((astrology) a person who is born while the sun is in Cancer) 3. Cancer -- (a small zodiacal constellation in the northern hemisphere; between Leo and Gemini) 4. Cancer, Cancer the Crab, Crab -- (the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22) 5. Cancer, genus Cancer -- (type genus of the family Cancridae) --- WordNet end ---