ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for cell out of >500 occurrences
928965 occurrences (No.3 in the rank) during 5 years in the PubMed. [no cache] 500 found
16) Human esophageal adenocarcinoma (EAC) cell lines have made a substantial contribution to elucidating mechanisms of carcinogenesis and drug discovery.
--- ABSTRACT ---
PMID:23795680 DOI:10.1111/dote.12095
2015 Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
* Translational research on esophageal adenocarcinoma: from cell line to clinic.
- Human esophageal adenocarcinoma (EAC) cell lines have made a substantial contribution to elucidating mechanisms of carcinogenesis and drug discovery. Model research on EAC relies almost entirely on a relatively small set of established tumor cell lines because appropriate animal models are lacking. Nowadays, more than 20% of all fundamental translational research studies regarding EAC are partially or entirely based on these cell lines. The ready availability of these cell lines to investigators worldwide have resulted in more than 250 publications, including many examples of important biomedical discoveries. The high genomic similarities (but certainly not completely identical) between the EAC cell lines and their original tumors provide rational for their use. Recently, in a collaborative effort all available EAC cell lines have been verified resulting in the establishment of a reliable panel of 10 EAC cell lines. It could be expected that the value of these cell lines increases as unlimited source of tumor material because new biomedical techniques require more tumor cells and the supply of viable tumor cells is diminishing because of neoadjuvant chemo(radio)therapy of patients with EAC. Here, we review the history of the EAC cell lines and their utility in translational research and biomedical discovery.
--- ABSTRACT END ---
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(1)30 lines (19)5 tumour (37)3 migration (55)2 lymphoma,
(2)16 death (20)4 (RBC) (38)3 response (56)2 matrices
(3)15 proliferation (21)4 growth (39)3 scaffolds (57)2 numbers
(4)15 viability (22)4 markers (40)3 source (58)2 of
(5)13 lymphoma (23)4 nuclear (41)3 tumors (59)2 printing
(6)12 and (24)4 phenotype (42)3 type (60)2 responses
(7)9 carcinoma (25)4 populations (43)3 viability, (61)2 seeding
(8)9 culture (26)4 therapies (44)2 activation (62)2 survival
(9)9 sheets (27)3 adhesion, (45)2 aggregation (63)2 system
(10)9 transplantation (28)3 division (46)2 attachment (64)2 that
(11)9 types (29)3 energy (47)2 biology (65)2 therapy,
(12)8 adhesion (30)3 expansion (48)2 coating, (66)2 to
(13)8 cycle (31)3 growth, (49)2 death, (67)2 transplantation,
(14)8 therapy (32)3 immunity (50)2 density (68)2 tumours
(15)7 differentiation (33)3 infiltration (51)2 factors (69)2 types,
(16)7 proliferation, (34)3 line, (52)2 genes (70)2 volume
(17)6 surface (35)3 lines, (53)2 interactions (71)2 wall
(18)5 line (36)3 lung (54)2 invasion (72)2 was

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--- WordNet output for cell --- =>密室, 細胞, 電池, 独房・細胞, 監房, 組織, 独房 Overview of noun cell The noun cell has 7 senses (first 3 from tagged texts) 1. (71) cell -- (any small compartment; "the cells of a honeycomb") 2. (44) cell -- ((biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals) 3. (1) cell, electric cell -- (a device that delivers an electric current as the result of a chemical reaction) 4. cell, cadre -- (a small unit serving as part of or as the nucleus of a larger political movement) 5. cellular telephone, cellular phone, cellphone, cell, mobile phone -- (a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver) 6. cell, cubicle -- (small room in which a monk or nun lives) 7. cell, jail cell, prison cell -- (a room where a prisoner is kept) --- WordNet end ---