ELIZA

return kwic search for cell out of >500 occurrences
928965 occurrences (No.3 in the rank) during 5 years in the PubMed. [cache]

212) The mechanism of fibrosis involves many different cellular pathways, but the major cell type involved appears to be hepatic stellate cells.

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PMID:32713091 DOI:10.1002/wsbm.1499

2021 WIREs mechanisms of disease

* Liver fibrosis: Pathophysiology and clinical implications.

- Liver fibrosis is a clinically significant finding that has major impacts on patient morbidity and mortality. The mechanism of fibrosis involves many different cellular pathways, but the major cell type involved appears to be hepatic stellate cells. Many liver diseases, including Hepatitis B, C, and fatty liver disease cause ongoing hepatocellular damage leading to liver fibrosis. No matter the cause of liver disease, liver-related mortality increases exponentially with increasing fibrosis. The progression to cirrhosis brings more dramatic mortality and higher incidence of hepatocellular carcinoma. Fibrosis can also affect outcomes following liver transplantation in adult and pediatric patients and require retransplantation. Drugs exist to treat Hepatitis B and C that reverse fibrosis in patients with those viral diseases, but there are currently no therapies to directly treat liver fibrosis. Several mouse models of chronic liver diseases have been successfully reversed using novel drug targets with current therapies focusing mostly on prevention of myofibroblast activation. Further research in these areas could lead to development of drugs to treat fibrosis, which will have invaluable impact on patient survival. This article is categorized under: Metabolic Diseases > Molecular and Cellular Physiology.

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[frequency of next (right) word to cell]

(1)23 death	(18)5 differentiation	(35)3 envelope	(52)2 immunity
(2)15 lines	(19)5 infiltration	(36)3 function	(53)2 informative
(3)15 types	(20)5 membrane	(37)3 growth	(54)2 interactions
(4)14 proliferation	(21)4 null	(38)3 lysis	(55)2 is
(5)14 wall	(22)4 activation	(39)3 migration	(56)2 killing
(6)8 carcinoma	(23)4 apoptosis	(40)3 mitochondrial	(57)2 malignancies
(7)8 transplantation	(24)4 culture	(41)3 shape	(58)2 manner
(8)7 line	(25)4 cultures	(42)3 therapy	(59)2 marker
(9)7 lung	(26)4 invasion	(43)2 DNA	(60)2 mass
(10)7 populations	(27)4 metabolism	(44)2 adhesion,	(61)2 migration,
(11)7 proliferation,	(28)4 receptor	(45)2 behavior	(62)2 mixture
(12)7 viability	(29)4 responses	(46)2 biology	(63)2 morphology
(13)6 surface	(30)4 type	(47)2 cholesterol	(64)2 nuclear
(14)6 survival	(31)3 RNA	(48)2 culture,	(65)2 number
(15)6 types,	(32)3 adhesion	(49)2 development	(66)2 over-activation,
(16)5 and	(33)3 cycle	(50)2 fate	(67)2 permeability
(17)5 cycle,	(34)3 division	(51)2 genes

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--- WordNet output for cell --- =>密室, 細胞, 電池, 独房・細胞, 監房, 組織, 独房 Overview of noun cell The noun cell has 7 senses (first 3 from tagged texts) 1. (71) cell -- (any small compartment; "the cells of a honeycomb") 2. (44) cell -- ((biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals) 3. (1) cell, electric cell -- (a device that delivers an electric current as the result of a chemical reaction) 4. cell, cadre -- (a small unit serving as part of or as the nucleus of a larger political movement) 5. cellular telephone, cellular phone, cellphone, cell, mobile phone -- (a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver) 6. cell, cubicle -- (small room in which a monk or nun lives) 7. cell, jail cell, prison cell -- (a room where a prisoner is kept) --- WordNet end ---