ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for cell out of >500 occurrences
928965 occurrences (No.3 in the rank) during 5 years in the PubMed. [no cache] 500 found
262) In non-cytotoxic concentrations, in vitro assessment of the immunotoxic effects displayed moderate but significant suppression of proliferative activity of T-lymphocytes and T-dependent B-cell response in cultures stimulated with PWM > CON A, and no changes in PHA cultures.
--- ABSTRACT ---
PMID:23859252 DOI:10.3109/17435390.2013.816798
2015 Nanotoxicology
* Immunotoxicity and genotoxicity testing of PLGA-PEO nanoparticles in human blood cell model.
- A human blood cell model for immunotoxicity and genotoxicity testing was used to measure the response to polylactic-co-glycolic acid (PLGA-PEO) nanoparticle (NP) (0.12, 3, 15 and 75 μg/cm(2) exposure in fresh peripheral whole blood cultures/isolated peripheral blood mononuclear cell cultures from human volunteers (n = 9-13). PLGA-PEO NPs were not toxic up to dose 3 μg/cm(2); dose of 75 μg/cm(2) displays significant decrease in [(3)H]-thymidine incorporation into DNA of proliferating cells after 4 h (70% of control) and 48 h (84%) exposure to NPs. In non-cytotoxic concentrations, in vitro assessment of the immunotoxic effects displayed moderate but significant suppression of proliferative activity of T-lymphocytes and T-dependent B-cell response in cultures stimulated with PWM In non-cytotoxic concentrations, in vitro assessment of the immunotoxic effects displayed moderate but significant suppression of proliferative activity of T-lymphocytes and T-dependent B-cell response in cultures stimulated with PWM > CON A, and no changes in PHA cultures.gt; CON A, and no changes in PHA cultures. Decrease in proliferative function was the most significant in T-cells stimulated with CD3 antigen (up to 84%). Cytotoxicity of natural killer cells was suppressed moderately (92%) but significantly in middle-dosed cultures (4 h exposure). On the other hand, in low PLGA-PEO NPs dosed cultures, significant stimulation of phagocytic activity of granulocytes (119%) > monocytes (117%) and respiratory burst of phagocytes (122%) was recorded. Genotoxicity assessment revealed no increase in the number of micronucleated binucleated cells and no induction of SBs or oxidised DNA bases in PLGA-PEO-treated cells. To conclude on immuno- and genotoxicity of PLGA-PEO NPs, more experiments with various particle size, charge and composition need to be done.
--- ABSTRACT END ---
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[frequency of next (right) word to cell]
(1)30 lines (19)5 tumour (37)3 migration (55)2 lymphoma,
(2)16 death (20)4 (RBC) (38)3 response (56)2 matrices
(3)15 proliferation (21)4 growth (39)3 scaffolds (57)2 numbers
(4)15 viability (22)4 markers (40)3 source (58)2 of
(5)13 lymphoma (23)4 nuclear (41)3 tumors (59)2 printing
(6)12 and (24)4 phenotype (42)3 type (60)2 responses
(7)9 carcinoma (25)4 populations (43)3 viability, (61)2 seeding
(8)9 culture (26)4 therapies (44)2 activation (62)2 survival
(9)9 sheets (27)3 adhesion, (45)2 aggregation (63)2 system
(10)9 transplantation (28)3 division (46)2 attachment (64)2 that
(11)9 types (29)3 energy (47)2 biology (65)2 therapy,
(12)8 adhesion (30)3 expansion (48)2 coating, (66)2 to
(13)8 cycle (31)3 growth, (49)2 death, (67)2 transplantation,
(14)8 therapy (32)3 immunity (50)2 density (68)2 tumours
(15)7 differentiation (33)3 infiltration (51)2 factors (69)2 types,
(16)7 proliferation, (34)3 line, (52)2 genes (70)2 volume
(17)6 surface (35)3 lines, (53)2 interactions (71)2 wall
(18)5 line (36)3 lung (54)2 invasion (72)2 was

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--- WordNet output for cell --- =>密室, 細胞, 電池, 独房・細胞, 監房, 組織, 独房 Overview of noun cell The noun cell has 7 senses (first 3 from tagged texts) 1. (71) cell -- (any small compartment; "the cells of a honeycomb") 2. (44) cell -- ((biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals) 3. (1) cell, electric cell -- (a device that delivers an electric current as the result of a chemical reaction) 4. cell, cadre -- (a small unit serving as part of or as the nucleus of a larger political movement) 5. cellular telephone, cellular phone, cellphone, cell, mobile phone -- (a hand-held mobile radiotelephone for use in an area divided into small sections, each with its own short-range transmitter/receiver) 6. cell, cubicle -- (small room in which a monk or nun lives) 7. cell, jail cell, prison cell -- (a room where a prisoner is kept) --- WordNet end ---