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return kwic search for control out of >500 occurrences
399456 occurrences (No.44 in the rank) during 5 years in the PubMed. [no cache] 500 found

131) We also investigated potential differences in the morphology, density, or dynamics of dendritic spines in layer I/II primary sensory cortex of control and BGS alcohol exposed mice.

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PMID:34228891 DOI:10.1002/dneu.22843

2021 Developmental neurobiology

* Dynamics of microglia and dendritic spines in early adolescent cortex after developmental alcohol exposure.

- Fetal alcohol spectrum disorder patients suffer from many cognitive disabilities. These include impaired auditory, visual, and tactile sensory information processing, making it more difficult for these patients to learn to navigate social scenarios. Rodent studies have shown that alcohol exposure during the brain growth spurt (BGS) can lead to acute neuronal apoptosis and an immunological response by microglia in the somatosensory cortex. Since microglia have critical physiological functions, including the support of excitatory synapse remodeling via interactions with dendritic spines, we sought to understand whether BGS alcohol exposure has long-term effects on microglial or dendritic spine dynamics. Using in vivo two-photon microscopy in 4-5 week old mice, we evaluated microglial functions such as process motility, the response to tissue injury, and the dynamics of physical interactions between microglial processes and dendritic spines. We also investigated potential differences in the morphology, density, or dynamics of dendritic spines in layer I/II primary sensory cortex of control and BGS alcohol exposed mice. We found that microglial process motility and contact with dendritic spines were not altered after BGS alcohol exposure. While the response of microglial processes toward tissue injury was not significantly altered by prior alcohol exposure, there was a trend suggesting that alcohol early in life may prime microglia to respond more quickly to secondary injury. Spine density, morphology, stability, and remodeling over time were not perturbed after BGS alcohol exposure. We demonstrate that after BGS alcohol exposure, the physiological functions of microglia and excitatory neurons remain intact in early adolescence.

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(1)44 of	(13)6 with	(25)3 groups;	(37)2 for
(2)42 group	(14)5 condition	(26)3 measures,	(38)2 is
(3)39 null	(15)5 group,	(27)3 strategies	(39)2 it
(4)39 and	(16)4 animals	(28)3 study,	(40)2 mice,
(5)13 the	(17)4 but	(29)3 system	(41)2 network
(6)12 in	(18)4 or	(30)3 to	(42)2 outfit
(7)10 groups	(19)4 study	(31)3 trial	(43)2 powder,
(8)10 studies	(20)4 trials	(32)2 are	(44)2 samples
(9)8 measures	(21)3 banding	(33)2 as	(45)2 studies,
(10)8 mice	(22)3 cells	(34)2 clones,	(46)2 that
(11)7 over	(23)3 circuit	(35)2 conditions	(47)2 their
(12)6 subjects	(24)3 disease	(36)2 efforts	(48)2 treatment

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--- WordNet output for control --- =>1.管理する, 制御する, 統制する, 抑える, 2.コントロール, 実験対象, 管理, 対照標準 Overview of noun control The noun control has 11 senses (first 9 from tagged texts) 1. (19) control -- (power to direct or determine; "under control") 2. (16) control -- (a relation of constraint of one entity (thing or person or group) by another; "measures for the control of disease"; "they instituted controls over drinking on campus") 3. (7) control -- ((physiology) regulation or maintenance of a function or action or reflex etc; "the timing and control of his movements were unimpaired"; "he had lost control of his sphincters") 4. (5) control condition, control -- (a standard against which other conditions can be compared in a scientific experiment; "the control condition was inappropriate for the conclusions he wished to draw") 5. (5) control -- (the activity of managing or exerting control over something; "the control of the mob by the police was admirable") 6. (4) dominance, ascendance, ascendence, ascendancy, ascendency, control -- (the state that exists when one person or group has power over another; "her apparent dominance of her husband was really her attempt to make him pay attention to her") 7. (3) restraint, control -- (discipline in personal and social activities; "he was a model of polite restraint"; "she never lost control of herself") 8. (2) command, control, mastery -- (great skillfulness and knowledge of some subject or activity; "a good command of French") 9. (1) control, controller -- (a mechanism that controls the operation of a machine; "the speed controller on his turntable was not working properly"; "I turned the controls over to her") 10. control -- (a spiritual agency that is assumed to assist the medium during a seance) 11. control -- (the economic policy of controlling or limiting or curbing prices or wages etc.; "they wanted to repeal all the legislation that imposed economic controls") Overview of verb control The verb control has 8 senses (first 4 from tagged texts) 1. (28) control, command -- (exercise authoritative control or power over; "control the budget"; "Command the military forces") 2. (20) control, hold in, hold, contain, check, curb, moderate -- (lessen the intensity of; temper; hold in restraint; hold or keep within limits; "moderate your alcohol intake"; "hold your tongue"; "hold your temper"; "control your anger") 3. (7) operate, control -- (handle and cause to function; "do not operate machinery after imbibing alcohol"; "control the lever") 4. (1) manipulate, keep in line, control -- (control (others or oneself) or influence skillfully, usually to one's advantage; "She manipulates her boss"; "She is a very controlling mother and doesn't let her children grow up"; "The teacher knew how to keep the class in line"; "she keeps in line") 5. control, verify -- (check or regulate (a scientific experiment) by conducting a parallel experiment or comparing with another standard; "Are you controlling for the temperature?") 6. control -- (verify by using a duplicate register for comparison; "control an account") 7. see, check, insure, see to it, ensure, control, ascertain, assure -- (be careful or certain to do something; make certain of something; "He verified that the valves were closed"; "See that the curtains are closed"; "control the quality of the product") 8. master, control -- (have a firm understanding or knowledge of; be on top of; "Do you control these data?") --- WordNet end ---