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399456 occurrences (No.44 in the rank) during 5 years in the PubMed. [cache]

203) These results showed how a technique allowing control of porosity, pore design, and external shape of a ceramic bone substitute may be valuable for producing synthetic bone grafts with good clinical performances.

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PMID:23829685 DOI:10.1563/AAID-JOI-D-13-00053

2015 The Journal of oral implantology

* In Vivo Behavior of a Custom-Made 3D Synthetic Bone Substitute in Sinus Augmentation Procedures in Sheep.

- In this study, the in vivo behavior of a custom-made three-dimensional (3D) synthetic bone substitute was evaluated when used as scaffold for sinus augmentation procedures in an animal model. The scaffold was a calcium phosphate ceramic fabricated by the direct rapid prototyping technique, dispense-plotting. The geometrical and chemical properties of the scaffold were first analyzed through light and electron scanning microscopes, helium picnometer, and semi-quantitative X-ray diffraction measurements. Then, 6 sheep underwent monolateral sinus augmentation with the fabricated scaffolds. The animals were euthanized after healing periods of 45 and 90 days, and block sections including the grafted area were obtained. Bone samples were subjected to micro computerized tomography, morphological and histomorphometric analyses. A complete integration of the scaffold was reported, with abundant deposition of newly formed bone tissue within the biomaterial pores. Moreover, initial foci of bone remodeling were mainly localized at the periphery of the implanted area after 45 days, while continuous bridges of mature lamellar bone were recorded in 90-day specimens. This evidence supports the hypothesis that bone regeneration proceeds from the periphery to the center of the sinus cavity. These results showed how a technique allowing control of porosity, pore design, and external shape of a ceramic bone substitute may be valuable for producing synthetic bone grafts with good clinical performances.

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(1)96 group	(11)5 measures	(21)3 region,	(31)2 eyes
(2)34 and	(12)5 participants	(22)3 system	(32)2 levels
(3)29 null	(13)4 (P	(23)3 was	(33)2 mice
(4)29 region	(14)4 in	(24)3 with	(34)2 milk-LNS,
(5)24 of	(15)4 is	(25)2 NP	(35)2 practices
(6)21 groups	(16)4 over	(26)2 activities	(36)2 strategies
(7)17 group,	(17)4 regions	(27)2 but	(37)2 were
(8)9 the	(18)4 subjects	(28)2 donkeys
(9)7 group)	(19)3 a	(29)2 donkeys,
(10)7 study	(20)3 or	(30)2 during

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--- WordNet output for control --- =>1.管理する, 制御する, 統制する, 抑える, 2.コントロール, 実験対象, 管理, 対照標準 Overview of noun control The noun control has 11 senses (first 9 from tagged texts) 1. (19) control -- (power to direct or determine; "under control") 2. (16) control -- (a relation of constraint of one entity (thing or person or group) by another; "measures for the control of disease"; "they instituted controls over drinking on campus") 3. (7) control -- ((physiology) regulation or maintenance of a function or action or reflex etc; "the timing and control of his movements were unimpaired"; "he had lost control of his sphincters") 4. (5) control condition, control -- (a standard against which other conditions can be compared in a scientific experiment; "the control condition was inappropriate for the conclusions he wished to draw") 5. (5) control -- (the activity of managing or exerting control over something; "the control of the mob by the police was admirable") 6. (4) dominance, ascendance, ascendence, ascendancy, ascendency, control -- (the state that exists when one person or group has power over another; "her apparent dominance of her husband was really her attempt to make him pay attention to her") 7. (3) restraint, control -- (discipline in personal and social activities; "he was a model of polite restraint"; "she never lost control of herself") 8. (2) command, control, mastery -- (great skillfulness and knowledge of some subject or activity; "a good command of French") 9. (1) control, controller -- (a mechanism that controls the operation of a machine; "the speed controller on his turntable was not working properly"; "I turned the controls over to her") 10. control -- (a spiritual agency that is assumed to assist the medium during a seance) 11. control -- (the economic policy of controlling or limiting or curbing prices or wages etc.; "they wanted to repeal all the legislation that imposed economic controls") Overview of verb control The verb control has 8 senses (first 4 from tagged texts) 1. (28) control, command -- (exercise authoritative control or power over; "control the budget"; "Command the military forces") 2. (20) control, hold in, hold, contain, check, curb, moderate -- (lessen the intensity of; temper; hold in restraint; hold or keep within limits; "moderate your alcohol intake"; "hold your tongue"; "hold your temper"; "control your anger") 3. (7) operate, control -- (handle and cause to function; "do not operate machinery after imbibing alcohol"; "control the lever") 4. (1) manipulate, keep in line, control -- (control (others or oneself) or influence skillfully, usually to one's advantage; "She manipulates her boss"; "She is a very controlling mother and doesn't let her children grow up"; "The teacher knew how to keep the class in line"; "she keeps in line") 5. control, verify -- (check or regulate (a scientific experiment) by conducting a parallel experiment or comparing with another standard; "Are you controlling for the temperature?") 6. control -- (verify by using a duplicate register for comparison; "control an account") 7. see, check, insure, see to it, ensure, control, ascertain, assure -- (be careful or certain to do something; make certain of something; "He verified that the valves were closed"; "See that the curtains are closed"; "control the quality of the product") 8. master, control -- (have a firm understanding or knowledge of; be on top of; "Do you control these data?") --- WordNet end ---