ELIZA

return kwic search for control out of >500 occurrences
399456 occurrences (No.44 in the rank) during 5 years in the PubMed. [cache]

342) Thus, HDID mice may find a moderate dose of alcohol to be less aversive than control mice and consequently may drink more because of this reduced aversive sensitivity.

--- ABSTRACT ---

PMID:23910826 DOI:10.1111/adb.12079

2015 Addiction biology

* Rewarding and aversive effects of ethanol in High Drinking in the Dark selectively bred mice.

- Both rewarding and aversive effects contribute to alcohol consumption. Animals genetically predisposed to be high drinkers show reduced sensitivity to the aversive effects of alcohol, and in some instances, increased sensitivity to alcohol's rewarding effects. The present studies tested the high drinking in the dark (HDID) selected lines, a genetic model of drinking to intoxication, to determine whether intake in these mice was genetically related to sensitivity to alcohol aversion or reward. Male HDID mice from the first and second replicate lines (HDID-1 and HDID-2, respectively) and mice from the heterogeneous progenitor control population (HS/Npt, or HS) were conditioned for a taste aversion to a salt solution using two doses of alcohol, and lithium chloride (LiCl) and saline controls. In separate experiments, male and female HDID-1, HDID-2 and HS mice were conditioned for place preference using alcohol. HDID mice were found to have an attenuated sensitivity to alcohol at a moderate (2 g/kg) dose compared to HS mice, but did not differ on conditioned taste aversion to a high (4 g/kg) dose or LiCl or saline injections. HDID and HS mice showed comparable development of alcohol-induced conditioned place preference. These results indicate that high blood alcohol levels after drinking in the HDID mice is genetically related to attenuated aversion to alcohol, while sensitivity to alcohol reward is not altered in these mice. Thus, HDID mice may find a moderate dose of alcohol to be less aversive than control mice and consequently may drink more because of this reduced aversive sensitivity.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to control]

(1)96 group	(11)5 measures	(21)3 region,	(31)2 eyes
(2)34 and	(12)5 participants	(22)3 system	(32)2 levels
(3)29 null	(13)4 (P	(23)3 was	(33)2 mice
(4)29 region	(14)4 in	(24)3 with	(34)2 milk-LNS,
(5)24 of	(15)4 is	(25)2 NP	(35)2 practices
(6)21 groups	(16)4 over	(26)2 activities	(36)2 strategies
(7)17 group,	(17)4 regions	(27)2 but	(37)2 were
(8)9 the	(18)4 subjects	(28)2 donkeys
(9)7 group)	(19)3 a	(29)2 donkeys,
(10)7 study	(20)3 or	(30)2 during

add keyword

--- WordNet output for control --- =>1.管理する, 制御する, 統制する, 抑える, 2.コントロール, 実験対象, 管理, 対照標準 Overview of noun control The noun control has 11 senses (first 9 from tagged texts) 1. (19) control -- (power to direct or determine; "under control") 2. (16) control -- (a relation of constraint of one entity (thing or person or group) by another; "measures for the control of disease"; "they instituted controls over drinking on campus") 3. (7) control -- ((physiology) regulation or maintenance of a function or action or reflex etc; "the timing and control of his movements were unimpaired"; "he had lost control of his sphincters") 4. (5) control condition, control -- (a standard against which other conditions can be compared in a scientific experiment; "the control condition was inappropriate for the conclusions he wished to draw") 5. (5) control -- (the activity of managing or exerting control over something; "the control of the mob by the police was admirable") 6. (4) dominance, ascendance, ascendence, ascendancy, ascendency, control -- (the state that exists when one person or group has power over another; "her apparent dominance of her husband was really her attempt to make him pay attention to her") 7. (3) restraint, control -- (discipline in personal and social activities; "he was a model of polite restraint"; "she never lost control of herself") 8. (2) command, control, mastery -- (great skillfulness and knowledge of some subject or activity; "a good command of French") 9. (1) control, controller -- (a mechanism that controls the operation of a machine; "the speed controller on his turntable was not working properly"; "I turned the controls over to her") 10. control -- (a spiritual agency that is assumed to assist the medium during a seance) 11. control -- (the economic policy of controlling or limiting or curbing prices or wages etc.; "they wanted to repeal all the legislation that imposed economic controls") Overview of verb control The verb control has 8 senses (first 4 from tagged texts) 1. (28) control, command -- (exercise authoritative control or power over; "control the budget"; "Command the military forces") 2. (20) control, hold in, hold, contain, check, curb, moderate -- (lessen the intensity of; temper; hold in restraint; hold or keep within limits; "moderate your alcohol intake"; "hold your tongue"; "hold your temper"; "control your anger") 3. (7) operate, control -- (handle and cause to function; "do not operate machinery after imbibing alcohol"; "control the lever") 4. (1) manipulate, keep in line, control -- (control (others or oneself) or influence skillfully, usually to one's advantage; "She manipulates her boss"; "She is a very controlling mother and doesn't let her children grow up"; "The teacher knew how to keep the class in line"; "she keeps in line") 5. control, verify -- (check or regulate (a scientific experiment) by conducting a parallel experiment or comparing with another standard; "Are you controlling for the temperature?") 6. control -- (verify by using a duplicate register for comparison; "control an account") 7. see, check, insure, see to it, ensure, control, ascertain, assure -- (be careful or certain to do something; make certain of something; "He verified that the valves were closed"; "See that the curtains are closed"; "control the quality of the product") 8. master, control -- (have a firm understanding or knowledge of; be on top of; "Do you control these data?") --- WordNet end ---