ELIZA

return kwic search for disease out of >500 occurrences
422715 occurrences (No.39 in the rank) during 5 years in the PubMed. [cache]

237) The expected value of the amount of information a diagnostic test will provide is equal to the "mutual information" between the test result and the disease state.

--- ABSTRACT ---

PMID:22368178 DOI:10.1177/0962280212439742

2015 Statistical methods in medical research

* The channel capacity of a diagnostic test as a function of test sensitivity and test specificity.

- We apply the information theory concept of "channel capacity" to diagnostic test performance and derive an expression for channel capacity in terms of test sensitivity and test specificity. The expected value of the amount of information a diagnostic test will provide is equal to the "mutual information" between the test result and the disease state. For the case in which only two test results and two disease states are considered, mutual information, I(D;R), is a function of sensitivity, specificity, and the pretest probability of disease. The channel capacity of the test is the maximal value of I(D;R) for a given sensitivity and specificity. After deriving an expression for I(D;R) in terms of sensitivity, specificity, and pretest probability, we solve for the value of pretest probability that maximizes I(D;R). Channel capacity is obtained by using this value of pretest probability to calculate I(D;R). Channel capacity provides a convenient and meaningful single parameter measure of diagnostic test performance. It quantifies the upper limit of the amount of information a diagnostic test can be expected to provide about a patient's disease state.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to disease]

(1)100 null	(17)4 (PD)	(33)3 to	(49)2 condition,
(2)39 and	(18)4 activity	(34)2 (CHD)	(50)2 development
(3)16 is	(19)4 outcome	(35)2 (COPD)	(51)2 interval
(4)13 in	(20)4 severity,	(36)2 (CVD),	(52)2 many
(5)12 of	(21)4 the	(37)2 (GERD)	(53)2 multi-sectoral
(6)9 (FMD)	(22)4 who	(38)2 (LSD)	(54)2 on
(7)8 risk	(23)3 (CAD)	(39)2 (SC)	(55)2 onset
(8)7 severity	(24)3 compared	(40)2 Control	(56)2 onset,
(9)6 progression	(25)3 control	(41)2 activity,	(57)2 outbreaks
(10)6 that	(26)3 course	(42)2 are	(58)2 patterns
(11)6 was	(27)3 free	(43)2 as	(59)2 phobia
(12)5 (CVD)	(28)3 has	(44)2 associated	(60)2 prevention
(13)5 or	(29)3 management	(45)2 burden	(61)2 processes
(14)5 state	(30)3 may	(46)2 by	(62)2 progression,
(15)4 (AD)	(31)3 patients	(47)2 can	(63)2 surveillance
(16)4 (HD)	(32)3 states	(48)2 characterized	(64)2 usually

add keyword

--- WordNet output for disease --- =>病気, 病弊, 精神の退廃 Overview of noun disease The noun disease has 1 sense (first 1 from tagged texts) 1. (26) disease -- (an impairment of health or a condition of abnormal functioning) --- WordNet end ---