ELIZA

return kwic search for disease out of >500 occurrences
422715 occurrences (No.39 in the rank) during 5 years in the PubMed. [no cache] 500 found

240) Alzheimer's disease (AD) is a neurodegenerative disorder of the central nervous system.

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PMID:23823143 DOI:10.1177/1533317513495107

2015 American journal of Alzheimer's disease and other dementias

* Elevated Galectin-3 Levels in the Serum of Patients With Alzheimer's Disease.

- Alzheimer's disease (AD) is a neurodegenerative disorder of the central nervous system. Galectin-3 (Gal-3) is characterized by a conserved sequence within the carbohydrate recognition domain. The effect of Gal-3 in AD is presently unknown. In this study, we found significantly increased Gal-3 serum levels in patients with AD compared to control participants (P=.017). There was no significant difference between patients with mild cognitive impairment (MCI) and healthy controls (P=.143) or between patients with AD and MCI (P=.688). The degree of cognitive impairment, as measured by the Mini-Mental Status Examination score, was found to have a significant correlation with the Gal-3 serum levels in all patients and healthy controls. These data suggest that Gal-3 potentially plays a role in the neuropathogenesis of AD. The Gal-3 found in serum could be a potential candidate for a biomarker panel for AD diagnosis.

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[frequency of next (right) word to disease]

(1)100 null	(17)4 (PD)	(33)3 to	(49)2 condition,
(2)39 and	(18)4 activity	(34)2 (CHD)	(50)2 development
(3)16 is	(19)4 outcome	(35)2 (COPD)	(51)2 interval
(4)13 in	(20)4 severity,	(36)2 (CVD),	(52)2 many
(5)12 of	(21)4 the	(37)2 (GERD)	(53)2 multi-sectoral
(6)9 (FMD)	(22)4 who	(38)2 (LSD)	(54)2 on
(7)8 risk	(23)3 (CAD)	(39)2 (SC)	(55)2 onset
(8)7 severity	(24)3 compared	(40)2 Control	(56)2 onset,
(9)6 progression	(25)3 control	(41)2 activity,	(57)2 outbreaks
(10)6 that	(26)3 course	(42)2 are	(58)2 patterns
(11)6 was	(27)3 free	(43)2 as	(59)2 phobia
(12)5 (CVD)	(28)3 has	(44)2 associated	(60)2 prevention
(13)5 or	(29)3 management	(45)2 burden	(61)2 processes
(14)5 state	(30)3 may	(46)2 by	(62)2 progression,
(15)4 (AD)	(31)3 patients	(47)2 can	(63)2 surveillance
(16)4 (HD)	(32)3 states	(48)2 characterized	(64)2 usually

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--- WordNet output for disease --- =>病気, 病弊, 精神の退廃 Overview of noun disease The noun disease has 1 sense (first 1 from tagged texts) 1. (26) disease -- (an impairment of health or a condition of abnormal functioning) --- WordNet end ---