ELIZA

return kwic search for disease out of >500 occurrences
422715 occurrences (No.39 in the rank) during 5 years in the PubMed. [no cache] 500 found

243) Huntington's disease (HD) is a devastating autosomal dominant neurodegenerative disease, caused by expansion of the CAG repeat in the huntingtin (HTT) gene and characterized pathologically by the loss of pyramidal neurons in several cortical areas, of striatal medium spiny neurons, and of hypothalamic neurons.

--- ABSTRACT ---

PMID:24277342 DOI:10.1007/7854_2013_250

2015 Current topics in behavioral neurosciences

* Therapeutic Strategies for Huntington's Disease.

- Huntington's disease (HD) is a devastating autosomal dominant neurodegenerative disease, caused by expansion of the CAG repeat in the huntingtin (HTT) gene and characterized pathologically by the loss of pyramidal neurons in several cortical areas, of striatal medium spiny neurons, and of hypothalamic neurons. Clinically, a distinguishing feature of the disease is uncontrolled involuntary movements (chorea, dyskensias) accompanied by progressive cognitive, motor, and psychiatric impairment. This review focuses on the current state of therapeutic development for the treatment of HD, including the preclinical and clinical development of small molecules and molecular therapies.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to disease]

(1)100 null	(17)4 (PD)	(33)3 to	(49)2 condition,
(2)39 and	(18)4 activity	(34)2 (CHD)	(50)2 development
(3)16 is	(19)4 outcome	(35)2 (COPD)	(51)2 interval
(4)13 in	(20)4 severity,	(36)2 (CVD),	(52)2 many
(5)12 of	(21)4 the	(37)2 (GERD)	(53)2 multi-sectoral
(6)9 (FMD)	(22)4 who	(38)2 (LSD)	(54)2 on
(7)8 risk	(23)3 (CAD)	(39)2 (SC)	(55)2 onset
(8)7 severity	(24)3 compared	(40)2 Control	(56)2 onset,
(9)6 progression	(25)3 control	(41)2 activity,	(57)2 outbreaks
(10)6 that	(26)3 course	(42)2 are	(58)2 patterns
(11)6 was	(27)3 free	(43)2 as	(59)2 phobia
(12)5 (CVD)	(28)3 has	(44)2 associated	(60)2 prevention
(13)5 or	(29)3 management	(45)2 burden	(61)2 processes
(14)5 state	(30)3 may	(46)2 by	(62)2 progression,
(15)4 (AD)	(31)3 patients	(47)2 can	(63)2 surveillance
(16)4 (HD)	(32)3 states	(48)2 characterized	(64)2 usually

add keyword

--- WordNet output for disease --- =>病気, 病弊, 精神の退廃 Overview of noun disease The noun disease has 1 sense (first 1 from tagged texts) 1. (26) disease -- (an impairment of health or a condition of abnormal functioning) --- WordNet end ---