ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for disease out of >500 occurrences
422715 occurrences (No.39 in the rank) during 5 years in the PubMed. [no cache] 500 found
31) Haplogroups A was implicated as a risk factor for AgP, while haplogroups D exhibited a protective effect in this disease.
--- ABSTRACT ---
PMID:24117188 DOI:10.3109/19401736.2013.840589
2015 Mitochondrial DNA
* Association of mitochondrial DNA displacement loop polymorphisms and aggressive periodontitis in a Chinese population: a pilot study.
- To examine whether certain mitochondrial DNA (mtDNA) haplogroups and/or alterations affect susceptibility to aggressive periodontitis (AgP), we analyzed the mtDNA D-Loop region in a Han Chinese population. The mtDNA haplogroups were analyzed in 58 patients with AgP and 50 periodontally healthy controls. The frequency of haplogroups A in AgP group was significantly higher than that in the control group (p=0.007). Furthermore, the frequency of haplogroup D was higher in the control group than that in AgP group (p=0.007). The frequencies of D-Loop polymorphisms m.16126T>C, m.16290C>T and m.152 T> C were significantly higher in patients with AgP compared with controls (p=0.029, 0.014 and 0.022, respectively). Additionally, the frequencies of three other D-Loop polymorphisms, m.16223C>T m.489 T>C and m.515CA deletion (del) were significantly lower in patients with AgP compared with controls (p=0.042, 0.003 and 0.026, respectively). Our study showed for the first time, an association between AgP and mtDNA haplogroups. Haplogroups A was implicated as a risk factor for AgP, while haplogroups D exhibited a protective effect in this disease. These observations may provide a new perspective on the study of the pathogenesis of periodontitis.
--- ABSTRACT END ---
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(1)100 *null* (17)4 (PD) (33)3 to (49)2 condition,
(2)39 and (18)4 activity (34)2 (CHD) (50)2 development
(3)16 is (19)4 outcome (35)2 (COPD) (51)2 interval
(4)13 in (20)4 severity, (36)2 (CVD), (52)2 many
(5)12 of (21)4 the (37)2 (GERD) (53)2 multi-sectoral
(6)9 (FMD) (22)4 who (38)2 (LSD) (54)2 on
(7)8 risk (23)3 (CAD) (39)2 (SC) (55)2 onset
(8)7 severity (24)3 compared (40)2 Control (56)2 onset,
(9)6 progression (25)3 control (41)2 activity, (57)2 outbreaks
(10)6 that (26)3 course (42)2 are (58)2 patterns
(11)6 was (27)3 free (43)2 as (59)2 phobia
(12)5 (CVD) (28)3 has (44)2 associated (60)2 prevention
(13)5 or (29)3 management (45)2 burden (61)2 processes
(14)5 state (30)3 may (46)2 by (62)2 progression,
(15)4 (AD) (31)3 patients (47)2 can (63)2 surveillance
(16)4 (HD) (32)3 states (48)2 characterized (64)2 usually

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--- WordNet output for disease --- =>病気, 病弊, 精神の退廃 Overview of noun disease The noun disease has 1 sense (first 1 from tagged texts) 1. (26) disease -- (an impairment of health or a condition of abnormal functioning) --- WordNet end ---