ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for due to out of >500 occurrences
319715 occurrences (No.67 in the rank) during 5 years in the PubMed. [no cache] 500 found
245) Development to term of interspecies cloned yak embryos has not been achieved, possibly due to abnormal epigenetic reprogramming.
--- ABSTRACT ---
PMID:23759515 DOI:10.1017/S0967199413000245
2015 Zygote (Cambridge, England)
* Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns.
- Interspecies somatic cell nuclear transfer (iSCNT), a powerful tool in basic scientific research, has been used widely to increase and preserve the population of endangered species. Yak (Bos grunniens) is one of these species. Development to term of interspecies cloned yak embryos has not been achieved, possibly due to abnormal epigenetic reprogramming. Previous studies have demonstrated that treatment of intraspecies cloned embryos with (NaBu) significantly improves nuclear-cytoplasmic reprogramming and viability in vitro. Therefore, in this study, we evaluated the effect of optimal NaBu concentration and exposure time on preimplantation development of yak iSCNT embryos and on the expression patterns of developmentally important genes. The results showed that 8-cell rate, blastocyst formation rate and total cell number increased significantly compared with their untreated counterparts when yak iSCNT embryos were treated with 5 nM NaBu for 12 h after activation, but that the 2-cell stage embryo rate was not significantly different. The treatment of NaBu also increased significantly the expression levels of Oct-4 and decreased the expression levels of HDAC-2, Dnmt-1 and IGF-1; the expression patterns of these genes were more similar to that of their bovine-yak in vitro fertilization (BY-IVF) counterparts. The results described above indicated that NaBu treatment improved developmental competence in vitro and 'corrected' the gene expression patterns of yak iSCNT embryos.
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[frequency of next (right) word to due to]
(1)115 the (10)4 insufficient (19)2 cardiac (28)2 pannus
(2)30 its (11)3 changes (20)2 common (29)2 potential
(3)30 their (12)3 increased (21)2 condom (30)2 previous
(4)20 a (13)3 low (22)2 environmental (31)2 primary
(5)9 an (14)3 multiple (23)2 extreme (32)2 progressive
(6)5 limited (15)3 poor (24)2 inadequate (33)2 prolonged
(7)4 differences (16)3 possible (25)2 inflammation (34)2 similarities
(8)4 different (17)2 abnormal (26)2 lack (35)2 some
(9)4 high (18)2 anthropogenic (27)2 major

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--- WordNet output for due --- =>1.予定の, 支払期日がきて, 当然支払われるべき, 2.支払[提出]期日, 満期日, 会費 Overview of noun due The noun due has 2 senses (first 1 from tagged texts) 1. (4) due -- (that which is deserved or owed; "give the devil his due") 2. due -- (a payment that is due (e.g., as the price of membership); "the society dropped him for non-payment of dues") Overview of adj due The adj due has 4 senses (first 2 from tagged texts) 1. (6) due -- (owed and payable immediately or on demand; "payment is due") 2. (1) due -- (scheduled to arrive; "the train is due in 15 minutes") 3. due -- (suitable to or expected in the circumstances; "all due respect"; "due cause to honor them"; "a long due promotion"; "in due course"; "due esteem"; "exercising due care") 4. ascribable, due, imputable, referable -- (capable of being assigned or credited to; "punctuation errors ascribable to careless proofreading"; "the cancellation of the concert was due to the rain"; "the oversight was not imputable to him") Overview of adv due The adv due has 1 sense (no senses from tagged texts) 1. due -- (directly or exactly; straight; "went due North") --- WordNet end ---