ELIZA

return kwic search for expression of out of >500 occurrences
286252 occurrences (No.88 in the rank) during 5 years in the PubMed. [cache]

154) The expression of cytokines/chemokines in meningiomas has been studied to some extent, and some of them form autocrine loops in the tumour cells.

--- ABSTRACT ---

PMID:34503077 DOI:10.3390/cancers13174267

2021 Cancers

* Meningioma-Brain Crosstalk: A Scoping Review.

- Background: In recent years, it has become evident that the tumoral microenvironment (TME) plays a key role in the pathogenesis of various cancers. In meningiomas, however, the TME is poorly understood, and it is unknown if glia cells contribute to meningioma growth and behaviour. Objective: This scoping review investigates if the literature describes and substantiates tumour-brain crosstalk in meningiomas and summarises the current evidence regarding the role of the brain parenchyma in the pathogenesis of meningiomas. Methods: We identified studies through the electronic database PubMed. Articles describing glia cells and cytokines/chemokines in meningiomas were selected and reviewed. Results: Monocytes were detected as the most abundant infiltrating immune cells in meningiomas. Only brain-invasive meningiomas elicited a monocytic response at the tumour-brain interface. The expression of cytokines/chemokines in meningiomas has been studied to some extent, and some of them form autocrine loops in the tumour cells. Paracrine interactions between tumour cells and glia cells have not been explored. Conclusion: It is unknown to what extent meningiomas elicit an immune response in the brain parenchyma. We speculate that tumour-brain crosstalk might only be relevant in cases of invasive meningiomas that disrupt the pial-glial basement membrane.

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(1)32 the	(13)4 mutant	(24)2 KIF20B	(36)2 heat
(2)18 genes	(14)4 specific	(25)2 Ki-67	(37)2 miR-296
(4)8 a	(15)3 many	(26)2 MMP-1	(38)2 miR-627
(5)7 these	(16)3 mitochondrial	(27)2 NCS1	(39)2 miRNAs
(6)6 nuclear	(17)3 multiple	(29)2 SLCO2B1	(40)2 oncoproteins,
(7)5 Staphylococcus	(18)3 several	(30)2 VEGF	(41)2 platelet-derived
(8)5 pro-inflammatory	(19)3 vascular	(31)2 asSuGR,	(42)2 recombinant
(9)4 CYP3A4	(20)2 ACE-2	(32)2 cytokines/chemokines	(43)2 tight
(10)4 both	(21)2 ASIC1a,	(33)2 farnesoid
(11)4 inflammatory	(22)2 ATG5	(34)2 fibroblast
(12)4 its	(23)2 CCN1	(35)2 fibrogenic

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--- WordNet output for expression --- =>表現すること, 式, 表現, 表示, 言い回し, 表現法, 表情 Overview of noun expression The noun expression has 9 senses (first 6 from tagged texts) 1. (23) expression, look, aspect, facial expression, face -- (the feelings expressed on a person's face; "a sad expression"; "a look of triumph"; "an angry face") 2. (18) expression, manifestation, reflection, reflexion -- (expression without words; "tears are an expression of grief"; "the pulse is a reflection of the heart's condition") 3. (15) expression, verbal expression, verbalism -- (the communication (in speech or writing) of your beliefs or opinions; "expressions of good will"; "he helped me find verbal expression for my ideas"; "the idea was immediate but the verbalism took hours") 4. (5) saying, expression, locution -- (a word or phrase that particular people use in particular situations; "pardon the expression") 5. (4) formulation, expression -- (the style of expressing yourself; "he suggested a better formulation"; "his manner of expression showed how much he cared") 6. (4) formula, expression -- (a group of symbols that make a mathematical statement) 7. expression -- ((genetics) the process of expressing a gene) 8. construction, grammatical construction, expression -- (a group of words that form a constituent of a sentence and are considered as a single unit; "I concluded from his awkward constructions that he was a foreigner") 9. expression -- (the act of forcing something out by squeezing or pressing; "the expression of milk from her breast") --- WordNet end ---