* Dose-dependent effects of metals on gene expression in the sydney rock oyster, Saccostrea glomerata.
- In the current study, we tested the effects of common environmental contaminants (the metals zinc and lead) on gene expression in Sydney rock oysters (Saccrostrea glomerata). Oysters were exposed to a range of metal concentrations under controlled laboratory conditions. The expression of 14 putative stress response genes was then measured using quantitative, real-time (q) PCR. The expression of all 14 genes was significantly affected (p < 0.05 vs. nonexposed controls) by at least one of the metals, and by at least one dose of metal. For 5 of the 14 target genes (actin, calmodulin, superoxide dismutase, topoisomerase I, and tubulin) the alteration of expression relative to controls was highest at intermediate (rather than high) doses of metals. Such responses may reflect adaptive (acclimation) reactions in gene expression at low to intermediate doses of contaminants, followed by a decline in expression resulting from exposure at higher doses. The data are discussed in terms of the intracellular pathways affected by metal contamination, and the relevance of such gene expression data to environmental biomonitoring.
=>表現すること, 式, 表現, 表示, 言い回し, 表現法, 表情
Overview of noun expression
The noun expression has 9 senses (first 6 from tagged texts)
1. (23) expression, look, aspect, facial expression, face -- (the feelings expressed on a person's
face; "a sad expression"; "a look of triumph"; "an angry face")
2. (18) expression, manifestation, reflection, reflexion -- (expression without words; "tears are an
expression of grief"; "the pulse is a reflection of the heart's condition")
3. (15) expression, verbal expression, verbalism -- (the communication (in speech or writing) of
your beliefs or opinions; "expressions of good will"; "he helped me find verbal expression for my
ideas"; "the idea was immediate but the verbalism took hours")
4. (5) saying, expression, locution -- (a word or phrase that particular people use in particular
situations; "pardon the expression")
5. (4) formulation, expression -- (the style of expressing yourself; "he suggested a better
formulation"; "his manner of expression showed how much he cared")
6. (4) formula, expression -- (a group of symbols that make a mathematical statement)
7. expression -- ((genetics) the process of expressing a gene)
8. construction, grammatical construction, expression -- (a group of words that form a constituent
of a sentence and are considered as a single unit; "I concluded from his awkward constructions that
he was a foreigner")
9. expression -- (the act of forcing something out by squeezing or pressing; "the expression of milk
from her breast")
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