ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for expression of out of >500 occurrences
286252 occurrences (No.88 in the rank) during 5 years in the PubMed. [no cache] 500 found
28) Following patient agreement to donate tissue samples to our biobank we catalogued the histological appearance, defined the expression of the hormone receptors ERα, PR, AR and the proliferation marker Ki67, and generated and characterised primary cell cultures in a female to male (FTM) transgender patient referred to our unit for surgery.
--- ABSTRACT ---
PMID:24715474 DOI:10.1007/s10561-014-9444-y
2015 Cell and tissue banking
* Adding value to rare tissue samples donated to biobanks: characterisation of breast tissue and primary cell cultures obtained from a female-to-male transgender patient.
- Biobanks provide a window of opportunity to store and add value to material from rare cases allowing their future use in biomedical research. One such example is the opportunityto obtain good quality tissue from patients undergoing gender re-assignment. Following patient agreement to donate tissue samples to our biobank we catalogued the histological appearance, defined the expression of the hormone receptors ERα, PR, AR and the proliferation marker Ki67, and generated and characterised primary cell cultures in a female to male (FTM) transgender patient referred to our unit for surgery. Immunohistochemistry was performed for ERα, PR and AR and the proliferation marker Ki67. Hormone receptor expression was confined to epithelial cells lining the breast ducts. Ki67 immunoreactivity was sparse indicating little proliferation of luminal epithelium, consistent with normal mammary gland. Cultures of epithelial cells and fibroblasts were derived from surplus tissue. The latter lacked expression of epithelial markers and hormone receptors but exhibited expression of vimentin. Culture of the former on Matrigel saw an outgrowth of more rounded "epithelial-like" cells. Immunofluoresence characterisation showed a mixed phenotype with expression of vimentin and both myoepithelial and luminal epithelial markers. Sporadic weak ERα expression and moderate PR expression was seen. In summary, as well as routinely collecting tissue and blood samples, we have characterised and stored tissue and cells from a FTM transgender patient, adding value to this resource which,available from the Breast Cancer Campaign Tissue Bank for those interested in further studying the biology of FTM transgender tissue.
--- ABSTRACT END ---
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[frequency of next (right) word to expression of]
(1)55 the (15)3 key (29)2 P-selectin, (44)2 cell
(2)11 a (16)3 multiple (30)2 P2X3 (45)2 constitutively
(3)9 genes (17)3 ncRAN (32)2 Sema (46)2 hyaluronan
(4)8 several (18)3 nicotine-induced (33)2 Siglec-9 (47)2 imprinted
(5)6 miR-218 (19)3 nuclear (34)2 TAF4 (48)2 intercellular
(6)5 these (20)3 specific (35)2 Wnt (49)2 membrane
(7)4 VEGF (21)3 this (36)2 acetyl-CoA (50)2 miR-128
(8)4 first (22)2 AdipoR1 (37)2 adhesion (51)2 napsin
(9)4 matrix (23)2 Caspase (38)2 adiponectin (52)2 phosphorylated
(10)3 CYP1A1 (24)2 FBP1 (39)2 angiogenic (53)2 piRNA-823
(11)3 DNMT1 (25)2 GABAA (40)2 anti-apoptotic (54)2 pro-inflammatory
(12)3 all (26)2 GLP-1R (41)2 b-FGF, (55)2 some
(13)3 cardiac (27)2 Ki-67, (42)2 c-Myc (56)2 three
(14)3 integrin (28)2 LOX-1 (43)2 cartilage

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--- WordNet output for expression --- =>表現すること, 式, 表現, 表示, 言い回し, 表現法, 表情 Overview of noun expression The noun expression has 9 senses (first 6 from tagged texts) 1. (23) expression, look, aspect, facial expression, face -- (the feelings expressed on a person's face; "a sad expression"; "a look of triumph"; "an angry face") 2. (18) expression, manifestation, reflection, reflexion -- (expression without words; "tears are an expression of grief"; "the pulse is a reflection of the heart's condition") 3. (15) expression, verbal expression, verbalism -- (the communication (in speech or writing) of your beliefs or opinions; "expressions of good will"; "he helped me find verbal expression for my ideas"; "the idea was immediate but the verbalism took hours") 4. (5) saying, expression, locution -- (a word or phrase that particular people use in particular situations; "pardon the expression") 5. (4) formulation, expression -- (the style of expressing yourself; "he suggested a better formulation"; "his manner of expression showed how much he cared") 6. (4) formula, expression -- (a group of symbols that make a mathematical statement) 7. expression -- ((genetics) the process of expressing a gene) 8. construction, grammatical construction, expression -- (a group of words that form a constituent of a sentence and are considered as a single unit; "I concluded from his awkward constructions that he was a foreigner") 9. expression -- (the act of forcing something out by squeezing or pressing; "the expression of milk from her breast") --- WordNet end ---