ELIZA

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403337 occurrences (No.43 in the rank) during 5 years in the PubMed. [no cache] 500 found

346) Here we present the characterization of the OPS structure and gene cluster of Y.

--- ABSTRACT ---

PMID:24361587 DOI:10.1177/1753425913514783

2015 Innate immunity

* Structure and genetic basis of Yersinia similis serotype O:9 O-specific polysaccharide.

- The O-polysaccharide (OPS, O-Ag) cap of LPS is a major virulence factor of Yersinia species and also serves as a receptor for the binding of lytic bacteriophage φR1-37. Currently, the OPS-based serotyping scheme for the Yersinia pseudotuberculosis complex includes 21 known O-serotypes that follow three distinct lineages: Y. pseudotuberculosis sensu stricto, Y. similis and the Korean group of strains. Elucidation of the Y. pseudotuberculosis complex OPS structures and characterization of the OPS genetics (altogether 18 O-serotypes studied thus far) allows a better understanding of the relationships among the various O serotypes and will facilitate the analysis of the evolutionary processes giving rise to new serotypes. Here we present the characterization of the OPS structure and gene cluster of Y. similis O:9. Bacteriophage φR1-37, which uses the Y. similis O:9 OPS as a receptor, also infects a number of Y. enterocolitica serotypes, including O:3, O:5,27, O:9 and O:50. The Y. similis O:9 OPS structure resembled none of the receptor structures of the Y. enterocolitica strains, suggesting that φR1-37 can recognize several surface receptors, thus promoting broad host specificity.

--- ABSTRACT END ---

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(1)75 expression	(15)5 of	(29)3 block	(43)2 mutation
(2)34 order	(16)5 transfer	(30)3 can	(44)2 on
(3)32 arrangement	(17)5 were	(31)3 contents	(45)2 overlap
(4)31 and	(18)4 activation	(32)3 polymorphisms	(46)2 peptide
(5)21 null	(19)4 delivery	(33)3 sequencing	(47)2 profiling
(6)15 was	(20)4 encoding	(34)3 transcription	(48)2 regions
(7)12 expression,	(21)4 expressions	(35)2 analysis	(49)2 sequence
(8)9 arrangement,	(22)4 fragments	(36)2 carriers	(50)2 sequences,
(9)7 composition	(23)4 is	(37)2 cluster	(51)2 spookier
(10)7 organization	(24)4 silencing	(38)2 clusters	(52)2 synteny
(11)7 sequences	(25)4 to	(39)2 content	(53)2 therapy,
(12)5 flow	(26)4 which	(40)2 family	(54)2 used
(13)5 for	(27)3 alterations	(41)2 from	(55)2 uses
(14)5 in	(28)3 as	(42)2 has

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--- WordNet output for gene --- =>遺伝子 Overview of noun gene The noun gene has 1 sense (no senses from tagged texts) 1. gene, cistron, factor -- ((genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors") --- WordNet end ---