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299409 occurrences (No.76 in the rank) during 5 years in the PubMed. [no cache] 500 found

402) Moreover, pESCs represent an important model system to study the effect of paternally imprinted genes on cell differentiation.

--- ABSTRACT ---

PMID:23798507 DOI:10.1002/term.1779

2015 Journal of tissue engineering and regenerative medicine

* Research with parthenogenetic stem cells will help decide whether a safer clinical use is possible.

- The derivation and use of parthenogenetic stem cells (pESCs) are envisaged as a reliable alternative to conventional embryonic stem cells. Similar to embryonic stem cells in their proliferation, expression of pluripotency markers and capacity to multilineage differentiation, pESCs are at a lower risk of immune rejection within stem cell-based therapeutics. Moreover, pESCs represent an important model system to study the effect of paternally imprinted genes on cell differentiation. However, currently available information about the genetic and epigenetic behaviour of pESCs is limited. Thus, a detailed look at the biology of parthenogenetic (PG) embryos and PG-derived cell lines would allow gaining insight into the full potential of pESC in biotechnology. In this commentary article we review some features related to the biology of PG embryos and pESCs. In addition, novel traits on bovine pESCs (bpESCs) are discussed.

--- ABSTRACT END ---

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[frequency of next (right) word to genes]

(1)101 and	(12)8 including	(23)4 for	(34)2 13
(2)36 null	(13)7 encoding	(24)4 from	(35)2 but
(3)28 are	(14)7 involved	(25)4 related	(36)2 can
(4)26 were	(15)7 which	(26)4 with	(37)2 coding
(5)25 in	(16)6 (PCGs),	(27)3 had	(38)2 expressed
(6)16 2	(17)6 use	(28)3 have	(39)2 is
(7)14 (13	(18)5 may	(29)3 stop	(40)2 on
(8)14 22	(19)5 that	(30)3 such	(41)2 ranged
(9)12 start	(20)4 (PCGs)	(31)2 (cytb,	(42)2 to
(10)11 of	(21)4 as	(32)2 (pnad1
(11)9 was	(22)4 associated	(33)2 (srfAA,

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--- WordNet output for genes --- =>発生, 起源, 起こり, 生成, 創始, 創世記 Overview of noun gene The noun gene has 1 sense (no senses from tagged texts) 1. gene, cistron, factor -- ((genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors") --- WordNet end ---