ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
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kwic search for human out of >500 occurrences
482327 occurrences (No.32 in the rank) during 5 years in the PubMed. [no cache]
500 found
289) Evidence from human studies as well as animal models have shown that alterations in nutrition and growth in utero and during early postnatal life can have permanent effects on systems mediating regulation of energy balance.
- As the prevalence of obesity increases across the globe, vast efforts are being directed towards understanding the origins of obesity and mechanisms underlying this rapid increase. It is well known that the current environment of an individual can affect body weight, however, growing evidence suggests that the environment in very early life may be particularly important in determining long term obesity risk. This was prompted by a series of epidemiological studies demonstrating a relationship between suboptimal early growth and later risk of obesity. Evidence from human studies as well as animal models have shown that alterations in nutrition and growth in utero and during early postnatal life can have permanent effects on systems mediating regulation of energy balance. Rapid postnatal growth in particular has been associated with increased risk of developing obesity while slower postnatal growth lowers this risk. Alterations in pathways mediating energy homeostasis have been associated with both patterns of early growth. These include changes in structure and function of neuronal pathways in the brain which lead to deregulation of pathways mediating energy balance. In addition to the alterations at the central level, early nutrition can have detrimental long-lasting effects on peripheral physiological systems, for example the storage of fat and utilization of nutrients that make an individual more prone to development of obesity. The fundamental mechanisms underlying these programmed changes are still to be fully defined, although epigenetic mechanisms may play an important role.
=>人間らしい, 人間の, 人, 人間
Overview of noun human
The noun human has 1 sense (first 1 from tagged texts)
1. (5) homo, man, human being, human -- (any living or extinct member of the family Hominidae
characterized by superior intelligence, articulate speech, and erect carriage)
Overview of adj human
The adj human has 3 senses (first 3 from tagged texts)
1. (46) human -- (characteristic of humanity; "human nature")
2. (19) human -- (relating to a person; "the experiment was conducted on 6 monkeys and 2 human
subjects")
3. (15) human -- (having human form or attributes as opposed to those of animals or divine beings;
"human beings"; "the human body"; "human kindness"; "human frailty")
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