ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for important out of >500 occurrences
448856 occurrences (No.37 in the rank) during 5 years in the PubMed. [cache]
262) Immunomodulation with drugs like omalizumab in IgE-mediated asthma syndromes is one important approach.
--- ABSTRACT ---
PMID:24178860 DOI:10.1007/s12016-013-8393-8
2015 Clinical reviews in allergy & immunology
* Pharmacotherapy of critical asthma syndrome: current and emerging therapies.
- The critical asthma syndrome (CAS) encompasses the most severe, persistent, refractory asthma patients for the clinician to manage. Personalized pharmacotherapy is necessary to prevent the next acute severe asthma exacerbation, not just the control of symptoms. The 2007 National Asthma Education and Prevention Program Expert Panel 3 provides guidelines for the treatment of uncontrolled asthma. The patient's response to recommended pharmacotherapy is highly variable which risks poor asthma control leading to frequent exacerbations that can deteriorate into CAS. Controlling asthma symptoms and preventing acute exacerbations may be two separate clinical activities with their own unique demands. Clinicians must be prepared to use the entire spectrum of asthma medications available but must concurrently be aware of potential drug toxicities some of which can paradoxically worsen asthma control. Medications normally prescribed for COPD can potentially be useful in the CAS patient, particularly those with asthma-COPD overlap syndrome. Immunomodulation with drugs like omalizumab in IgE-mediated asthma syndromes is one important approach. New and emerging drugs address unique aspects of airway inflammation and biology but at a significant financial cost. The pharmacology and toxicities of the agents that may be used in the treatment of CAS to control asthma symptoms and prevent severe exacerbations are reviewed.
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(1)65 role (16)4 data (31)2 alternative (46)2 indicator
(2)37 for (17)4 differences (32)2 aspect (47)2 mechanism
(3)34 to (18)3 approach (33)2 baseline (48)2 model
(4)28 in (19)3 causes (34)2 because (49)2 molecular
(5)15 implications (20)3 clinical (35)2 bivalve, (50)2 not
(6)11 factor (21)3 findings (36)2 complication (51)2 pathogen
(7)9 *null* (22)3 genes (37)2 components (52)2 phenomenon
(8)9 and (23)3 health (38)2 consequences (53)2 physiological
(9)8 determinants (24)3 human (39)2 contributor (54)2 protective
(10)8 roles (25)3 insights (40)2 coping (55)2 route
(11)7 factors (26)3 policy (41)2 determinant (56)2 standard
(12)6 cause (27)3 predictors (42)2 economic (57)2 step
(13)5 component (28)3 public (43)2 element (58)2 strategic
(14)5 risk (29)3 when (44)2 fish (59)2 subset
(15)4 as (30)2 DNA (45)2 function (60)2 target

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--- WordNet output for important --- =>重要な, 有力な, 重大な, 大切な Overview of adj important The adj important has 5 senses (first 4 from tagged texts) 1. (146) important, of import -- (of great significance or value; "important people"; "the important questions of the day") 2. (4) significant, important -- (important in effect or meaning; "a significant change in tax laws"; "a significant change in the Constitution"; "a significant contribution"; "significant details"; "statistically significant") 3. (2) crucial, important -- (of extreme importance; vital to the resolution of a crisis; "a crucial moment in his career"; "a crucial election"; "a crucial issue for women") 4. (1) authoritative, important -- (having authority or ascendancy or influence; "an important official"; "the captain's authoritative manner") 5. important -- (having or suggesting a consciousness of high position; "recited the decree with an important air"; "took long important strides in the direction of his office") --- WordNet end ---