ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for including out of >500 occurrences
468001 occurrences (No.36 in the rank) during 5 years in the PubMed. [no cache] 500 found
31) The P-gp has wide substrate specificity for multiple medications including the lipid lowering drug, atorvastatin.
--- ABSTRACT ---
PMID:24414406 DOI:10.1007/s10616-013-9682-z
2015 Cytotechnology
* The role of Multidrug Resistance-1 (MDR1) variants in response to atorvastatin among Jordanians.
- The MDR1 gene encodes for P-glycoprotein (P-gp), which is an efflux transporter at the cell membrane. The P-gp has wide substrate specificity for multiple medications including the lipid lowering drug, atorvastatin. In this study, we investigated the possible association between three common MDR1 gene polymorphisms (G2677T, C3435T, and C1236T), and the lipid lowering effect of atorvastatin among Jordanians. Lipid and lipoproteins were measured in blood samples collected from patients (n = 201) at baseline and during atorvastatin treatment. MDR1 polymorphisms were genotyped using polymerase chain reaction-restriction fragment length polymorphism. Both the TT genotype of G2677T and the TT genotype of the C3435T polymorphisms were associated with lower levels of low-density lipoproteins after atorvastatin treatment. However, the effects of atorvastatin on the levels of total cholesterol, triglycerides, and high-density lipoprotein, were not correlated with any of the genotypes in both polymorphisms. Finally, the C1236T polymorphism was not associated with the lipid lowering effect of atorvastatin. In conclusion, the MDR1 gene polymorphisms G2677T, and C3435T, but not C1236T were associated with the lipid lowering effect of atorvastatin among Jordanians.
--- ABSTRACT END ---
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(1)55 the (10)3 all (20)2 an (29)2 lower
(2)28 13 (11)3 cell (21)2 angiogenesis, (30)2 lung
(3)11 a (12)3 our (22)2 appropriate (31)2 many
(4)7 those (13)3 reduced (23)2 autism (32)2 questions
(5)5 in (14)3 their (24)2 changes (33)2 studies
(6)5 its (15)3 three (25)2 depression, (34)2 topical
(7)4 2 (17)2 3 (26)2 improved (35)2 two
(8)4 both (18)2 37 (27)2 increased
(9)3 age, (19)2 activated (28)2 induction

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--- WordNet output for including --- =>含む Overview of verb include The verb include has 4 senses (first 4 from tagged texts) 1. (234) include -- (have as a part, be made up out of; "The list includes the names of many famous writers") 2. (32) include -- (consider as part of something; "I include you in the list of culprits") 3. (18) include -- (add as part of something else; put in as part of a set, group, or category; "We must include this chemical element in the group") 4. (8) admit, let in, include -- (allow participation in or the right to be part of; permit to exercise the rights, functions, and responsibilities of; "admit someone to the profession"; "She was admitted to the New Jersey Bar") --- WordNet end ---