* Open-loop analysis on sympathetically mediated arterial pressure and urine output responses in spontaneously hypertensive rats: effect of renal denervation.
- Primary acute sympathetic activation (PASA) causes a subsequent arterial pressure (AP) elevation. In this case, an antidiuretic effect via the renal innervation and pressure diuresis can act antagonistically on the kidneys. We examined the effect of PASA on urine output in spontaneously hypertensive rats (SHR) 4-7 days after unilateral renal denervation (RDN) (n = 9). The slope of the plot of urine flow versus AP was positive (0.120 ± 0.031 μL min-1 kg-1 mmHg-1) on the intact side, but it was less than 1/3 of the slope observed previously in normotensive Wistar-Kyoto rats (WKY). RDN did not normalize the slope of urine flow versus AP (0.179 ± 0.025 μL min-1 kg-1 mmHg-1, P = 0.098 versus the intact side). The urine flow at the operating point of the AP tended to be greater on the denervated than the intact side (29.0 ± 1.8 vs. 25.3 ± 1.9 μL min-1 kg-1, P = 0.055). The percent increase (17.2 ± 7.2%) was not different from that observed previously in WKY. Although high-resting sympathetic nerve activity is prerequisite for maintaining hypertension in SHR, the effect of sympathetic innervation on the urine output function was not greater than that in WKY.
=>大きくなる, を増す, 増大させる, 強まる, 増加, 増える, 増やす
Overview of noun increase
The noun increase has 5 senses (first 5 from tagged texts)
1. (49) addition, increase, gain -- (a quantity that is added; "there was an addition to property
taxes this year"; "they recorded the cattle's gain in weight over a period of weeks")
2. (21) increase -- (a change resulting in an increase; "the increase is scheduled for next month")
3. (7) increase, increment, growth -- (a process of becoming larger or longer or more numerous or
more important; "the increase in unemployment"; "the growth of population")
4. (3) increase, increment -- (the amount by which something increases; "they proposed an increase
of 15 percent in the fare")
5. (3) increase, step-up -- (the act of increasing something; "he gave me an increase in salary")
Overview of verb increase
The verb increase has 2 senses (first 2 from tagged texts)
1. (86) increase -- (become bigger or greater in amount; "The amount of work increased")
2. (61) increase -- (make bigger or more; "The boss finally increased her salary"; "The university
increased the number of students it admitted")
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