ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for lower out of >500 occurrences
288686 occurrences (No.85 in the rank) during 5 years in the PubMed. [no cache] 500 found
2) The formulations were composed of particles with diameter lower than 355 μm.
--- ABSTRACT ---
PMID:24219826 DOI:10.3109/10837450.2013.852572
2015 Pharmaceutical development and technology
* Formulation and characterization study of itraconazole-loaded microparticles.
- The aim of the work was to realize itraconazole-loaded formulations in form of microparticles using a fast, simple and solvent free production procedure. The selected excipients were able to enhance wettability of the final product, to increase drug dissolution rate and to maintain drug in solution thanks to the formation of an emulsified system after contact with the gastrointestinal fluids. Itraconazole formulations contained a structuring lipid, a solubilizing agent and a surface active substance and were prepared by a hot melt method (MMS, melting-milling-sieving). The characterization included drug content determination, granulometric distribution, differential scanning calorimetry (DSC) and in vitro drug release test, physical and technological stability after 12 months of ambient condition storage. The formulations were composed of particles with diameter lower than 355 μm. DSC analysis evidenced that itraconazole was almost completely in the amorphous form; the results of the in vitro drug release tests showed that these formulations were able to increase the rate of the drug release compared to that of the free drug. Stability data showed no significant changes in the thermal and release profiles, confirming that the selected excipients protected the drug avoiding its conversion from amorphous state into crystalline form and maintaining unchanged the delivery behavior.
--- ABSTRACT END ---
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(1)38 than (19)4 incidence (37)3 socioeconomic (55)2 expression
(2)35 in (20)4 leg (38)3 stresses (56)2 eyelid
(3)19 levels (21)4 spine (39)3 values (57)2 eyelids
(4)12 extremity (22)4 total (40)2 Condom (58)2 frequencies
(5)11 risk (23)3 (P (41)2 EI (59)2 frequency
(6)7 compared (24)3 *null* (42)2 IQ (60)2 likelihood
(7)7 level (25)3 ASM/wt (43)2 abdominal (61)2 limit
(8)7 limb (26)3 education (44)2 among (62)2 microleakage
(9)5 at (27)3 educational (45)2 back (63)2 perceived
(10)5 for (28)3 extremities, (46)2 birthweight (64)2 percentage
(11)5 limbs (29)3 heart (47)2 bounds (65)2 quality
(12)5 the (30)3 initial (48)2 by (66)2 rate
(13)4 and (31)3 legs (49)2 complication (67)2 resilience
(14)4 body (32)3 mean (50)2 concentration (68)2 serum
(15)4 cervical (33)3 odds (51)2 concentrations (69)2 shear
(16)4 dose (34)3 prevalence (52)2 demineralization
(17)4 doses (35)3 probability (53)2 esophageal
(18)4 extremities (36)3 sexual (54)2 estimated

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--- WordNet output for lower --- =>1.低くする/なる, 下げる/下がる, 卑しめる, 2.しかめっ面, 3.lowの比較級 Overview of noun lower The noun lower has 1 sense (no senses from tagged texts) 1. lower berth, lower -- (the lower of two berths) Overview of verb lower The verb lower has 5 senses (first 3 from tagged texts) 1. (15) lower, take down, let down, get down, bring down -- (move something or somebody to a lower position; "take down the vase from the shelf") 2. (6) lower, lour -- (set lower; "lower a rating"; "lower expectations") 3. (1) turn down, lower, lour -- (make lower or quieter; "turn down the volume of a radio") 4. lower, depress -- (cause to drop or sink; "The lack of rain had depressed the water level in the reservoir") 5. frown, glower, lour, lower -- (look angry or sullen, wrinkle one's forehead, as if to signal disapproval) Overview of adj low The adj low has 10 senses (first 6 from tagged texts) 1. (55) low -- (less than normal in degree or intensity or amount; "low prices"; "the reservoir is low") 2. (23) low -- (literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow") 3. (11) low, low-toned -- (very low in volume; "a low murmur"; "the low-toned murmur of the surf") 4. (6) low -- (unrefined in character; "low comedy") 5. (4) low, low-pitched -- (used of sounds and voices; low in pitch or frequency) 6. (3) abject, low, low-down, miserable, scummy, scurvy -- (of the most contemptible kind; "abject cowardice"; "a low stunt to pull"; "a low-down sneak"; "his miserable treatment of his family"; "You miserable skunk!"; "a scummy rabble"; "a scurvy trick") 7. humble, low, lowly, modest, small -- (low or inferior in station or quality; "a humble cottage"; "a lowly parish priest"; "a modest man of the people"; "small beginnings") 8. depleted, low -- (no longer sufficient; "supplies are low"; "our funds are depleted") 9. broken, crushed, humbled, humiliated, low -- (subdued or brought low in condition or status; "brought low"; "a broken man"; "his broken spirit") 10. gloomy, grim, blue, depressed, dispirited, down, downcast, downhearted, down in the mouth, low, low-spirited -- (filled with melancholy and despondency ; "gloomy at the thought of what he had to face"; "gloomy predictions"; "a gloomy silence"; "took a grim view of the economy"; "the darkening mood"; "lonely and blue in a strange city"; "depressed by the loss of his job"; "a dispirited and resigned expression on her face"; "downcast after his defeat"; "feeling discouraged and downhearted") --- WordNet end ---