* Quantifying morphological alteration of RBC population from light scattering data.
- Studies of RBC morphological alterations, despite their potential clinical and experimental application, are compromised due to lack of simple and rapid techniques. As a complementary approach toward quantitative microscopy, we have reconstituted morphological information from light scattering data obtained from flow cytometer. Normal and poikilocytic agent treated samples were analyzed by microscopy and respective morphological index (MI) was calculated from the morphology based scores assigned to RBC. The samples were simultaneously analyzed by flowcytometer and the scatter data were obtained. Accordingly, the best correlated parameters of both forward scatter and side scatter were chosen to formulate a suitable regression model with MI as response. Flow cytometry data was also verified with another instrument (BD FACS Verse) and the equation obtained was validated with separate set of samples. The multivariate regression analysis yields a quadratic model with MI as response (R2 = 0.96, p < 0.001). The flow cytometric data from both instruments were in good agreement (Intra class correlation ∼0.9, p < 0.001). The model was found to simulate the sample MI with high accuracy (R2 = 0.97, p < 0.001). This proposed method was verified to be simple, rapid, quantitative and cost effective for the measurement of morphological alteration of RBC.
=>模型, 作る, 形に表わす, 模範, モデル, 型, 模型の, 模範となる, かたどる, 手本, モデルをする,
手本となる
Overview of noun model
The noun model has 9 senses (first 7 from tagged texts)
1. (19) model, theoretical account, framework -- (a hypothetical description of a complex entity or
process; "the computer program was based on a model of the circulatory and respiratory systems")
2. (11) model -- (a type of product; "his car was an old model")
3. (6) model, poser -- (a person who poses for a photographer or painter or sculptor; "the president
didn't have time to be a model so the artist worked from photos")
4. (4) model, simulation -- (representation of something (sometimes on a smaller scale))
5. (3) exemplar, example, model, good example -- (something to be imitated; "an exemplar of
success"; "a model of clarity"; "he is the very model of a modern major general")
6. (1) model, role model -- (someone worthy of imitation; "every child needs a role model")
7. (1) model, example -- (a representative form or pattern; "I profited from his example")
8. mannequin, manikin, mannikin, manakin, fashion model, model -- (a woman who wears clothes to
display fashions; "she was too fat to be a mannequin")
9. model, modelling, modeling -- (the act of representing something (usually on a smaller scale))
Overview of verb model
The verb model has 6 senses (first 2 from tagged texts)
1. (1) model, pattern -- (plan or create according to a model or models)
2. (1) model, mold, mould -- (form in clay, wax, etc; "model a head with clay")
3. model, pose, sit, posture -- (assume a posture as for artistic purposes; "We don't know the woman
who posed for Leonardo so often")
4. model -- (display (clothes) as a mannequin; "model the latest fashion")
5. model, simulate -- (create a representation or model of; "The pilots are trained in conditions
simulating high-altitude flights")
6. model, mock up -- (construct a model of; "model an airplane")
Overview of adj model
The adj model has 1 sense (first 1 from tagged texts)
1. (1) exemplary, model -- (worthy of imitation; "exemplary behavior"; "model citizens")
--- WordNet end ---