ELIZA

return kwic search for molecular out of >500 occurrences
333489 occurrences (No.56 in the rank) during 5 years in the PubMed. [cache]

141) In this review, we summarize the recent advances in the understanding of KSHV hijacking of metabolic pathways and sensors, providing insights into the molecular basis of KSHV infection and KSHV-induced oncogenesis.

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PMID:34579773 DOI:10.1186/s13578-021-00688-0

2021 Cell & bioscience

* Metabolic reprogramming and metabolic sensors in KSHV-induced cancers and KSHV infection.

- Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus associated with several human cancers. KSHV infection and KSHV-induced anabolic cell proliferation and cellular transformation depend on reprogramming of cellular metabolic pathways, which provide the building blocks and energy for the growth of both the virus and the infected cells. Furthermore, KSHV dysregulates numerous metabolic sensors including mTOR, AMPK, CASTOR1 and sirtuins to maintain cellular energetic homeostasis during infection and in KSHV-induced cancers. In this review, we summarize the recent advances in the understanding of KSHV hijacking of metabolic pathways and sensors, providing insights into the molecular basis of KSHV infection and KSHV-induced oncogenesis. In addition, we highlight the critical metabolic targets and sensors for developing potential new therapies against KSHV infection and KSHV-induced cancers.

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[frequency of next (right) word to molecular]

(1)65 mechanisms	(19)4 analysis	(37)3 pharmacological	(55)2 measurements
(2)25 dynamics	(20)4 level,	(38)3 profiling	(56)2 medicine
(3)20 and	(21)4 modeling	(39)3 recognition	(57)2 methods
(4)14 mechanism	(22)4 processes	(40)3 response	(58)2 monitoring
(5)13 docking	(23)4 properties	(41)2 actions	(59)2 pathways,
(6)12 basis	(24)4 testing	(42)2 biological	(60)2 rotational
(7)11 pathways	(25)3 cellular,	(43)2 characterisation	(61)2 signaling
(8)8 details	(26)3 characteristics	(44)2 clock	(62)2 signals
(9)7 level	(27)3 clock,	(45)2 crowding	(63)2 signature
(10)7 markers	(28)3 composition	(46)2 data	(64)2 signatures
(11)7 patterns	(29)3 diagnoses	(47)2 determinant	(65)2 subtype
(12)7 weight	(30)3 effects	(48)2 diagnosis	(66)2 supporting
(13)6 subtypes	(31)3 features	(49)2 distributions	(67)2 target
(14)6 targets	(32)3 genetic	(50)2 docking,	(68)2 to
(15)5 changes	(33)3 imaging	(51)2 efficacy	(69)2 trajectory
(16)5 characterization	(34)3 initiating	(52)2 genetic,
(17)5 determinants	(35)3 mechanism,	(53)2 identity
(18)5 events	(36)3 pathology	(54)2 investigations

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--- WordNet output for molecular --- =>分子の Overview of adj molecular The adj molecular has 2 senses (first 1 from tagged texts) 1. (6) molecular -- (relating to or produced by or consisting of molecules; "molecular structure"; "molecular oxygen"; "molecular weight is the sum of all the atoms in a molecule") 2. molecular -- (relating to simple or elementary organization; "proceed by more and more detailed analysis to the molecular facts of perception"--G.A. Miller) --- WordNet end ---