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486851 occurrences (No.30 in the rank) during 5 years in the PubMed. [no cache] 500 found

135) Many new targets including different components of cell wall, plasma membrane, tRNA, DNA and others in the sensitive cells for the killer toxin action have been identified so that the new molecular mechanisms of action have been elucidated.

--- ABSTRACT ---

PMID:24102112 DOI:10.3109/07388551.2013.833582

2015 Critical reviews in biotechnology

* Yeast killer toxins, molecular mechanisms of their action and their applications.

- Killer toxins secreted by some yeast strains are the proteins that kill sensitive cells of the same or related yeast genera. In recent years, many new yeast species have been found to be able to produce killer toxins against the pathogenic yeasts, especially Candida albicans. Some of the killer toxins have been purified and characterized, and the genes encoding the killer toxins have been cloned and characterized. Many new targets including different components of cell wall, plasma membrane, tRNA, DNA and others in the sensitive cells for the killer toxin action have been identified so that the new molecular mechanisms of action have been elucidated. However, it is still unknown how some of the newly discovered killer toxins kill the sensitive cells. Studies on the killer phenomenon in yeasts have provided valuable insights into a number of fundamental aspects of eukaryotic cell biology and interactions of different eukaryotic cells. Elucidation of the molecular mechanisms of their action will be helpful to develop the strategies to fight more and more harmful yeasts.

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[frequency of next (right) word to new]

(1)19 Zealand	(19)4 targets	(37)2 Zealand,	(55)2 important
(2)13 bone	(20)3 DP	(38)2 avenues	(56)2 innovations
(3)12 approach	(21)3 York,	(39)2 biomarkers	(57)2 instrument
(4)11 and	(22)3 approaches	(40)2 blood	(58)2 methodologies
(5)10 method	(23)3 concepts	(41)2 case	(59)2 methods
(6)9 insights	(24)3 information	(42)2 cases	(60)2 parameters
(7)7 York	(25)3 insight	(43)2 challenges	(61)2 policy
(8)7 therapeutic	(26)3 light	(44)2 co-processed	(62)2 public
(9)5 data	(27)3 media	(45)2 compound	(63)2 risk
(10)5 molecular	(28)3 molecules	(46)2 concept	(64)2 strategies
(11)5 species	(29)3 regulation	(47)2 diagnostic	(65)2 strategy
(12)4 World	(30)3 research	(48)2 driver	(66)2 subspecies
(13)4 class	(31)3 technique	(49)2 drug	(67)2 training
(14)4 clinical	(32)3 treatment	(50)2 endemic	(68)2 type
(15)4 discoveries	(33)2 Graves'	(51)2 evidence	(69)2 way
(16)4 generation	(34)2 HIV	(52)2 findings
(17)4 measure	(35)2 South	(53)2 genetic
(18)4 model	(36)2 York/Japan	(54)2 health

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--- WordNet output for new --- =>新発見の, 新しい, 現代的な, 新参の Overview of adj new The adj new has 11 senses (first 5 from tagged texts) 1. (310) new -- (not of long duration; having just (or relatively recently) come into being or been made or acquired or discovered; "a new law"; "new cars"; "a new comet"; "a new friend"; "a new year"; "the New World") 2. (36) fresh, new, novel -- (original and of a kind not seen before; "the computer produced a completely novel proof of a well-known theorem") 3. (11) raw, new -- (lacking training or experience; "the new men were eager to fight"; "raw recruits") 4. (5) new, unexampled -- (having no previous example or precedent or parallel; "a time of unexampled prosperity") 5. (3) new -- (other than the former one(s); different; "they now have a new leaders"; "my new car is four years old but has only 15,000 miles on it"; "ready to take a new direction") 6. new -- (unaffected by use or exposure; "it looks like new") 7. newfangled, new -- ((of a new kind or fashion) gratuitously new; "newfangled ideas"; "she buys all these new-fangled machines and never uses them") 8. New -- (in use after medieval times; "New Eqyptian was the language of the 18th to 21st dynasties") 9. Modern, New -- (used of a living language; being the current stage in its development; "Modern English"; "New Hebrew is Israeli Hebrew") 10. new, young -- ((of crops) harvested at an early stage of development; before complete maturity; "new potatoes"; "young corn") 11. new -- (unfamiliar; "new experiences"; "experiences new to him"; "errors of someone new to the job") Overview of adv new The adv new has 1 sense (first 1 from tagged texts) 1. (1) newly, freshly, fresh, new -- (very recently; "they are newly married"; "newly raised objections"; "a newly arranged hairdo"; "grass new washed by the rain"; "a freshly cleaned floor"; "we are fresh out of tomatoes") --- WordNet end ---