ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for new out of >500 occurrences
486851 occurrences (No.30 in the rank) during 5 years in the PubMed. [no cache] 500 found
14) These in vitro evaluations were followed by a proof-of-concept animal study involving implantation of scaffolds in proximal tibial growth plate defects in New Zealand white rabbits.
--- ABSTRACT ---
PMID:23239617 DOI:10.1002/term.1670
2015 Journal of tissue engineering and regenerative medicine
* Treatment of growth plate injury using IGF-I-loaded PLGA scaffolds.
- Growth plate fracture can lead to retarded growth and unequal limb length, which may have a lifelong effect on a person's physical stature. The goal of this research was to develop an in vivo tissue-engineering approach for the treatment of growth plate injury via localized delivery of insulin-like growth factor I (IGF-I) from cell-free poly(lactic-co-glycolic acid) (PLGA) scaffolds. Mass loss and drug release studies were conducted to study the scaffold degradation and IGF-I release patterns. In vitro cell studies showed that rat bone marrow stromal cells seeded on the porous scaffolds colonized the pores and deposited matrix within the scaffolds. These in vitro evaluations were followed by a proof-of-concept animal study involving implantation of scaffolds in proximal tibial growth plate defects in New Zealand white rabbits. Histological analysis of tissue sections from the in vivo studies showed regeneration of cartilage, albeit with disorganized structure, at the site of implantation of IGF-I-releasing scaffolds; in contrast, only bone was formed in empty defects and those treated with IGF-free scaffolds. The present findings show the potential for treating growth plate injury using in vivo tissue engineering techniques.
--- ABSTRACT END ---
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[frequency of next (right) word to new]
(1)19 Zealand (19)4 targets (37)2 Zealand, (55)2 important
(2)13 bone (20)3 DP (38)2 avenues (56)2 innovations
(3)12 approach (21)3 York, (39)2 biomarkers (57)2 instrument
(4)11 and (22)3 approaches (40)2 blood (58)2 methodologies
(5)10 method (23)3 concepts (41)2 case (59)2 methods
(6)9 insights (24)3 information (42)2 cases (60)2 parameters
(7)7 York (25)3 insight (43)2 challenges (61)2 policy
(8)7 therapeutic (26)3 light (44)2 co-processed (62)2 public
(9)5 data (27)3 media (45)2 compound (63)2 risk
(10)5 molecular (28)3 molecules (46)2 concept (64)2 strategies
(11)5 species (29)3 regulation (47)2 diagnostic (65)2 strategy
(12)4 World (30)3 research (48)2 driver (66)2 subspecies
(13)4 class (31)3 technique (49)2 drug (67)2 training
(14)4 clinical (32)3 treatment (50)2 endemic (68)2 type
(15)4 discoveries (33)2 Graves' (51)2 evidence (69)2 way
(16)4 generation (34)2 HIV (52)2 findings
(17)4 measure (35)2 South (53)2 genetic
(18)4 model (36)2 York/Japan (54)2 health

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--- WordNet output for new --- =>新発見の, 新しい, 現代的な, 新参の Overview of adj new The adj new has 11 senses (first 5 from tagged texts) 1. (310) new -- (not of long duration; having just (or relatively recently) come into being or been made or acquired or discovered; "a new law"; "new cars"; "a new comet"; "a new friend"; "a new year"; "the New World") 2. (36) fresh, new, novel -- (original and of a kind not seen before; "the computer produced a completely novel proof of a well-known theorem") 3. (11) raw, new -- (lacking training or experience; "the new men were eager to fight"; "raw recruits") 4. (5) new, unexampled -- (having no previous example or precedent or parallel; "a time of unexampled prosperity") 5. (3) new -- (other than the former one(s); different; "they now have a new leaders"; "my new car is four years old but has only 15,000 miles on it"; "ready to take a new direction") 6. new -- (unaffected by use or exposure; "it looks like new") 7. newfangled, new -- ((of a new kind or fashion) gratuitously new; "newfangled ideas"; "she buys all these new-fangled machines and never uses them") 8. New -- (in use after medieval times; "New Eqyptian was the language of the 18th to 21st dynasties") 9. Modern, New -- (used of a living language; being the current stage in its development; "Modern English"; "New Hebrew is Israeli Hebrew") 10. new, young -- ((of crops) harvested at an early stage of development; before complete maturity; "new potatoes"; "young corn") 11. new -- (unfamiliar; "new experiences"; "experiences new to him"; "errors of someone new to the job") Overview of adv new The adv new has 1 sense (first 1 from tagged texts) 1. (1) newly, freshly, fresh, new -- (very recently; "they are newly married"; "newly raised objections"; "a newly arranged hairdo"; "grass new washed by the rain"; "a freshly cleaned floor"; "we are fresh out of tomatoes") --- WordNet end ---