282) This is the longest reported follow-up of a patient being off steroids while on MMF. |
PMID:24075023 DOI:10.5414/CN108025 |
2015 Clinical nephrology |
* Mycophenolate mofetil as a steroid-sparing agent in sarcoid-associated renal disease. |
- Steroids are the mainstay of treatment for renal sarcoidosis. Many patients with sarcoidosis are chronically dependent on steroids and there is limited data on the use of steroid-sparing agents. This is a case of a patient that has remained in remission using mycophenolate mofetil (MMF) as a steroid-sparing agent. The patient is a 56-year-old female with a history of sarcoidosis diagnosed by lymph node biopsy who developed 3 episodes of acute kidney injury (AKI) in the setting of exacerbations of her sarcoidosis, each responding to prednisone treatment. Due to possible lifelong need for prednisone, MMF was started as a steroid-sparing treatment. She tolerated the MMF well and has now been steroidfree for 22 months. There have been only a few case reports about the use of MMF as a steroid-sparing agent in sarcoid-associated renal disease, in which patients could be successfully weaned off steroids. This is the longest reported follow-up of a patient being off steroids while on MMF. It is also notable for the patient having a relapse on the MMF which responded to an increased dose. MMF should be studied further as a potential steroid-sparing agent in the treatment of sarcoid associated renal disease. |
(1)52 with | (17)4 MSCs | (33)3 subsequently | (49)2 motivation |
(2)30 was | (18)4 education | (34)2 Education | (50)2 of |
(3)20 *null* | (19)4 presenting | (35)2 achieved | (51)2 outcome |
(4)18 and | (20)4 required | (36)2 age | (52)2 pain |
(5)15 had | (21)4 safety | (37)2 as | (53)2 population |
(6)12 who | (22)4 to | (38)2 assessment | (54)2 population, |
(7)11 care | (23)4 were | (39)2 being | (55)2 received |
(8)7 is | (24)3 characteristics | (40)2 can | (56)2 remained |
(9)7 survival | (25)3 comfort | (41)2 computational | (57)2 remains |
(10)7 underwent | (26)3 died | (42)2 data | (58)2 reported |
(11)6 developed | (27)3 group | (43)2 days | (59)2 response |
(12)6 outcomes | (28)3 information | (44)2 empowerment | (60)2 responses |
(13)6 satisfaction | (29)3 life | (45)2 factors, | (61)2 symptoms |
(14)5 groups | (30)3 on | (46)2 for | (62)2 the |
(15)5 in | (31)3 postoperative | (47)2 immunomigration | |
(16)5 presented | (32)3 referral | (48)2 including |
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