ELIZA

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404916 occurrences (No.41 in the rank) during 5 years in the PubMed. [no cache] 500 found

206) The FVL mutation in the heterozygous state was present in only 3 patients with SS disease and was absent in the controls.

--- ABSTRACT ---

PMID:23869056 DOI:10.1177/1076029613495308

2015 Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

* The Prevalence of Factor V Leiden (G1691A) and Methylenetetrahydrofolate Reductase C677T Mutations in Sickle Cell Disease in Western India.

- The prevalence of the Factor V Leiden (FVL; G1691A) mutation and the methylenetetrahydrofolate reductase (MTHFR; C677T) mutation was determined in 180 patients with sickle cell (SS) disease (126 sickle homozygous and 54 sickle β-thalassaemia--age 1-47 years) and in 130 healthy controls. The FVL mutation in the heterozygous state was present in only 3 patients with SS disease and was absent in the controls. Genotyping of MTHFR 677C > T revealed increased frequency of the C allele than the T allele in patients as well as in controls. This suggests that these genetic markers may not be major risk factors for a hypercoagulable state in Indian patients with SS disease.

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(1)23 chronic	(21)3 AD	(41)2 CAD	(61)2 critical
(2)13 a	(22)3 AgP	(42)2 CKD	(62)2 diabetes,
(3)10 diabetes	(23)3 CTD	(43)2 CVD	(63)2 early
(4)9 acute	(24)3 an	(44)2 DIC	(64)2 equal
(5)8 severe	(25)3 cardiovascular	(45)2 LGV	(65)2 hard-to-heal
(6)6 cancer	(26)3 comorbid	(46)2 MFS	(66)2 higher
(7)6 congenital	(27)3 end-stage	(47)2 NE	(67)2 ischemic
(8)5 RA	(28)3 fibromyalgia	(48)2 NSTE-ACS	(68)2 lesions
(9)5 and	(29)3 heart	(49)2 SS	(69)2 limited
(10)5 hypertension	(30)3 known	(50)2 SSc	(70)2 moderate
(11)5 type	(31)3 nonvalvular	(51)2 ST-segment	(71)2 no
(12)4 STEMI	(32)3 osteoarthritis	(52)2 VLUs	(72)2 normal
(13)4 advanced	(33)3 ovarian	(53)2 VTE	(73)2 pressure
(14)4 breast	(34)3 poor	(54)2 angina	(74)2 prior
(15)4 dementia	(35)3 schizophrenia	(55)2 antiheparin/PF4	(75)2 refractory
(16)4 low	(36)3 sickle	(56)2 asthma	(76)2 sarcoidosis
(17)4 sepsis	(37)3 symptomatic	(57)2 atrial	(77)2 somatoform
(18)4 stable	(38)3 the	(58)2 central	(78)2 stroke
(19)4 this	(39)2 AHA	(59)2 clinical	(79)2 sudden
(20)4 venous	(40)2 BD	(60)2 coronary

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--- WordNet output for patients --- Overview of noun patient The noun patient has 2 senses (first 1 from tagged texts) 1. (73) patient -- (a person who requires medical care; "the number of emergency patients has grown rapidly") 2. affected role, patient role, patient -- (the semantic role of an entity that is not the agent but is directly involved in or affected by the happening denoted by the verb in the clause) --- WordNet end ---