ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
return
kwic search for provide out of >500 occurrences
325270 occurrences (No.61 in the rank) during 5 years in the PubMed. [cache]
392) Our findings provide consistent evidence that the DISC1 Ser704Cys polymorphism influences the thalamic-prefrontal circuits in humans and may provide new insights into the neural mechanisms that link DISC1 and the risk for psychiatric disorders.
- The Disrupted-in-Schizophrenia 1 (DISC1) gene has been thought as a putative susceptibility gene for various psychiatric disorders, and DISC1 Ser704Cys is associated with variations of brain morphology and function. Moreover, our recent diffusion magnetic resonance imaging (dMRI) study reported that DISC1 Ser704Cys was associated with information transfer efficiency in the brain anatomical network. However, the effects of the DISC1 gene on functional brain connectivity and networks, especially for thalamic-prefrontal circuit, which are disrupted in various psychiatric disorders, are largely unknown. Using a functional connectivity density (FCD) mapping method based on functional magnetic resonance imaging data in a large sample of healthy Han Chinese subjects, we first investigated the association between DISC1 Ser704Cys and short- and long-range FCD hubs. Compared with Ser homozygotes, Cys-allele individuals had increased long-range FCD hubs in the bilateral thalami. The functional and anatomical connectivity of the thalamus to the prefrontal cortex was further analyzed. Significantly increased thalamic-prefrontal functional connectivity and decreased thalamic-prefrontal anatomical connectivity were found in DISC1 Cys-allele carriers. Our findings provide consistent evidence that the DISC1 Ser704Cys polymorphism influences the thalamic-prefrontal circuits in humans and may provide new insights into the neural mechanisms that link DISC1 and the risk for psychiatric disorders.
=>供給する, 与える, 規定する, 条件とする, 準備する, 用意する, 扶養する, 援助する
Overview of verb provide
The verb provide has 7 senses (first 4 from tagged texts)
1. (270) supply, provide, render, furnish -- (give something useful or necessary to; "We provided
the room with an electrical heater")
2. (25) provide, supply, ply, cater -- (give what is desired or needed, especially support, food or
sustenance; "The hostess provided lunch for all the guests")
3. (14) provide -- (determine (what is to happen in certain contingencies), especially by including
a proviso condition or stipulation; "The will provides that each child should receive half of the
money"; "The Constitution provides for the right to free speech")
4. (2) put up, provide, offer -- (mount or put up; "put up a good fight"; "offer resistance")
5. leave, allow for, allow, provide -- (make a possibility or provide opportunity for; permit to be
attainable or cause to remain; "This leaves no room for improvement"; "The evidence allows only one
conclusion"; "allow for mistakes"; "leave lots of time for the trip"; "This procedure provides for
lots of leeway")
6. provide, bring home the bacon -- (supply means of subsistence; earn a living; "He provides for
his large family by working three jobs"; "Women nowadays not only take care of the household but
also bring home the bacon")
7. provide -- (take measures in preparation for; "provide for the proper care of the passengers on
the cruise ship")
--- WordNet end ---