ELIZA

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273413 occurrences (No.92 in the rank) during 5 years in the PubMed. [no cache] 500 found

373) In the present study, the anxiety-related behavior was evaluated using the plus-maze test.

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PMID:23744884 DOI:10.1177/0748233713491802

2015 Toxicology and industrial health

* Effects of nanoparticle zinc oxide on emotional behavior and trace elements homeostasis in rat brain.

- Over recent years, nanotoxicology and the potential effects on human body have grown in significance, the potential influences of nanosized materials on the central nervous system have received more attention. The aim of this study was to determine whether zinc oxide (ZnO) nanoparticles (NPs) exposure cause alterations in emotional behavior and trace elements homeostasis in rat brain. Rats were treated by intraperitoneal injection of ZnO NPs (20-30 nm) at a dose of 25 mg/kg body weight. Sub -: acute ZnO NPs treatment induced no significant increase in the zinc content in the homogenate brain. Statistically significant decreases in iron and calcium concentrations were found in rat brain tissue compared to control. However, sodium and potassium contents remained unchanged. Also, there were no significant changes in the body weight and the coefficient of brain. In the present study, the anxiety-related behavior was evaluated using the plus-maze test. ZnO NPs treatment modulates slightly the exploratory behaviors of rats. However, no significant differences were observed in the anxious index between ZnO NP-treated rats and the control group (p > 0.05). Interestingly, our results demonstrated minimal effects of ZnO NPs on emotional behavior of animals, but there was a possible alteration in trace elements homeostasis in rat brain.

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(1)212 to	(11)4 and	(21)3 changes	(31)2 characteristics
(2)11 quality	(12)4 cognitions	(22)3 death	(32)2 genes,
(3)7 factors	(13)4 deaths	(23)3 disease	(33)2 head
(4)6 complications	(14)4 events	(24)3 functional	(34)2 hospital
(5)6 genes	(15)4 issues	(25)3 stress	(35)2 increases
(6)5 health	(16)4 macular	(26)3 symptoms	(36)2 parameters
(7)5 information	(17)4 osteonecrosis	(27)2 Anxiety	(37)2 proteins
(8)5 injuries	(18)4 with	(28)2 Cognitions	(38)2 psychosocial
(9)5 potentials	(19)3 activity	(29)2 barriers	(39)2 species
(10)4 activities	(20)3 cases	(30)2 brain

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--- WordNet output for related --- =>1.関係のある, 関連した, 2.同族の, 親類関係にある Overview of verb relate The verb relate has 5 senses (first 5 from tagged texts) 1. (15) associate, tie in, relate, link, colligate, link up, connect -- (make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all") 2. (9) refer, pertain, relate, concern, come to, bear on, touch, touch on, have-to doe with -- (be relevant to; "There were lots of questions referring to her talk"; "My remark pertained to your earlier comments") 3. (7) relate -- (give an account of; "The witness related the events") 4. (4) relate, interrelate -- (be in a relationship with; "How are these two observations related?") 5. (2) relate -- (have or establish a relationship to; "She relates well to her peers") Overview of adj related The adj related has 2 senses (first 2 from tagged texts) 1. (20) related, related to -- (being connected either logically or causally or by shared characteristics ; "painting and the related arts"; "school-related activities"; "related to micelle formation is the...ability of detergent actives to congregate at oil-water interfaces") 2. (4) related -- (connected by kinship, common origin, or marriage) --- WordNet end ---