ELIZA

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663834 occurrences (No.9 in the rank) during 5 years in the PubMed. [no cache] 500 found

360) We show here that conventional high-frequency tetanic stimulation (TS) of the auditory thalamus induced long-term changes in cortical field excitatory postsynaptic potentials, including both LTP and LTD, in mice.

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PMID:24046076 DOI:10.1093/cercor/bht259

2015 Cerebral cortex (New York, N.Y. : 1991)

* Physiological correspondence dictates cortical long-term potentiation and depression by thalamic induction.

- The auditory cortex exhibits frequency-specific plasticity over a life cycle. Although thalamocortical long-term potentiation (LTP) and depression (LTD) are components of a widely held model underlying the receptive field (RF) plasticity of cortical neurons, the model lacks direct supporting evidence. We show here that conventional high-frequency tetanic stimulation (TS) of the auditory thalamus induced long-term changes in cortical field excitatory postsynaptic potentials, including both LTP and LTD, in mice. Thalamic TS induced LTP when the stimulated thalamic and recorded cortical neurons were tuned to the same frequency and induced LTD when they were tuned to different frequencies. The thalamocortical LTP was N-methyl-d-aspartate-dependent, but the LTD also involved cortical γ-amino-butyric acidergic inhibition. Notably, the frequency-specificity of cortical LTP/LTD was in accordance with the frequency-specific plasticity of spike-based RFs of cortical neurons. Our results suggest that cortical LTP and LTD induced by thalamic induction can be a consequence of identical stimuli, occur in an input-specific manner, and account for frequency-specific remodeling of RFs of auditory cortical neurons.

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(1)255 that	(9)5 here	(17)3 different	(25)2 differences
(2)30 a	(10)5 promise	(18)3 risk	(26)2 differential
(3)24 the	(11)4 by	(19)3 statistically	(27)2 for
(4)13 how	(12)4 greater	(20)3 such	(28)2 great
(5)13 significant	(13)4 higher	(21)2 null	(29)2 important
(6)8 any	(14)4 increased	(22)2 beneficial	(30)2 lower
(7)8 that,	(15)4 more	(23)2 changes
(8)7 an	(16)4 similar	(24)2 clinical

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--- WordNet output for show --- =>教える, 見せること, 展覧会, 見世物, 外観, を見せる, を案内する, を明らかにする, 見える Overview of noun show The noun show has 4 senses (first 2 from tagged texts) 1. (18) show -- (the act of publicly exhibiting or entertaining; "a remarkable show of skill") 2. (9) display, show -- (something intended to communicate a particular impression; "made a display of strength"; "a show of impatience"; "a good show of looking interested") 3. show -- (a social event involving a public performance or entertainment; "they wanted to see some of the shows on Broadway") 4. appearance, show -- (pretending that something is the case in order to make a good impression; "they try to keep up appearances"; "that ceremony is just for show") Overview of verb show The verb show has 12 senses (first 11 from tagged texts) 1. (136) show, demo, exhibit, present, demonstrate -- (give an exhibition of to an interested audience; "She shows her dogs frequently"; "We will demo the new software in Washington") 2. (63) prove, demonstrate, establish, show, shew -- (establish the validity of something, as by an example, explanation or experiment; "The experiment demonstrated the instability of the compound"; "The mathematician showed the validity of the conjecture") 3. (57) testify, bear witness, prove, evidence, show -- (provide evidence for; "The blood test showed that he was the father"; "Her behavior testified to her incompetence") 4. (43) show -- (make visible or noticeable; "She showed her talent for cooking"; "Show me your etchings, please") 5. (32) picture, depict, render, show -- (show in, or as in, a picture; "This scene depicts country life"; "the face of the child is rendered with much tenderness in this painting") 6. (24) express, show, evince -- (give expression to; "She showed her disappointment") 7. (24) indicate, point, designate, show -- (indicate a place, direction, person, or thing; either spatially or figuratively; "I showed the customer the glove section"; "He pointed to the empty parking space"; "he indicated his opponents") 8. (11) show, show up -- (be or become visible or noticeable; "His good upbringing really shows"; "The dirty side will show") 9. (7) read, register, show, record -- (indicate a certain reading; of gauges and instruments; "The thermometer showed thirteen degrees below zero"; "The gauge read `empty'") 10. (6) show -- (give evidence of, as of records; "The diary shows his distress that evening") 11. (2) usher, show -- (take (someone) to their seats, as in theaters or auditoriums; "The usher showed us to our seats") 12. show -- (finish third or better in a horse or dog race; "he bet $2 on number six to show") --- WordNet end ---