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kwic search for show out of >500 occurrences
663834 occurrences (No.9 in the rank) during 5 years in the PubMed. [no cache]
500 found
380) Rodent electrophysiology studies have shown that as number of afferent fibers within a circuit decreases with age, the fibers that remain show higher synaptic field potentials (less wiring, more firing).
* Less wiring, more firing: low-performing older adults compensate for impaired white matter with greater neural activity.
- The reliable neuroimaging finding that older adults often show greater activity (over-recruitment) than younger adults is typically attributed to compensation. Yet, the neural mechanisms of over-recruitment in older adults (OAs) are largely unknown. Rodent electrophysiology studies have shown that as number of afferent fibers within a circuit decreases with age, the fibers that remain show higher synaptic field potentials (less wiring, more firing). Extrapolating to system-level measures in humans, we proposed and tested the hypothesis that greater activity in OAs compensates for impaired white-matter connectivity. Using a neuropsychological test battery, we measured individual differences in executive functions associated with the prefrontal cortex (PFC) and memory functions associated with the medial temporal lobes (MTLs). Using event-related functional magnetic resonance imaging, we compared activity for successful versus unsuccessful trials during a source memory task. Finally, we measured white-matter integrity using diffusion tensor imaging. The study yielded 3 main findings. First, low-executive OAs showed greater success-related activity in the PFC, whereas low-memory OAs showed greater success-related activity in the MTLs. Second, low-executive OAs displayed white-matter deficits in the PFC, whereas low-memory OAs displayed white-matter deficits in the MTLs. Finally, in both prefrontal and MTL regions, white-matter decline and success-related activations occurred in close proximity and were negatively correlated. This finding supports the less-wiring-more-firing hypothesis, which provides a testable account of compensatory over-recruitment in OAs.
=>教える, 見せること, 展覧会, 見世物, 外観, を見せる, を案内する, を明らかにする, 見える
Overview of noun show
The noun show has 4 senses (first 2 from tagged texts)
1. (18) show -- (the act of publicly exhibiting or entertaining; "a remarkable show of skill")
2. (9) display, show -- (something intended to communicate a particular impression; "made a display
of strength"; "a show of impatience"; "a good show of looking interested")
3. show -- (a social event involving a public performance or entertainment; "they wanted to see some
of the shows on Broadway")
4. appearance, show -- (pretending that something is the case in order to make a good impression;
"they try to keep up appearances"; "that ceremony is just for show")
Overview of verb show
The verb show has 12 senses (first 11 from tagged texts)
1. (136) show, demo, exhibit, present, demonstrate -- (give an exhibition of to an interested
audience; "She shows her dogs frequently"; "We will demo the new software in Washington")
2. (63) prove, demonstrate, establish, show, shew -- (establish the validity of something, as by an
example, explanation or experiment; "The experiment demonstrated the instability of the compound";
"The mathematician showed the validity of the conjecture")
3. (57) testify, bear witness, prove, evidence, show -- (provide evidence for; "The blood test
showed that he was the father"; "Her behavior testified to her incompetence")
4. (43) show -- (make visible or noticeable; "She showed her talent for cooking"; "Show me your
etchings, please")
5. (32) picture, depict, render, show -- (show in, or as in, a picture; "This scene depicts country
life"; "the face of the child is rendered with much tenderness in this painting")
6. (24) express, show, evince -- (give expression to; "She showed her disappointment")
7. (24) indicate, point, designate, show -- (indicate a place, direction, person, or thing; either
spatially or figuratively; "I showed the customer the glove section"; "He pointed to the empty
parking space"; "he indicated his opponents")
8. (11) show, show up -- (be or become visible or noticeable; "His good upbringing really shows";
"The dirty side will show")
9. (7) read, register, show, record -- (indicate a certain reading; of gauges and instruments; "The
thermometer showed thirteen degrees below zero"; "The gauge read `empty'")
10. (6) show -- (give evidence of, as of records; "The diary shows his distress that evening")
11. (2) usher, show -- (take (someone) to their seats, as in theaters or auditoriums; "The usher
showed us to our seats")
12. show -- (finish third or better in a horse or dog race; "he bet $2 on number six to show")
--- WordNet end ---