71) Especially, a significant increase from the control group to the DVT and PTE was observed in the analysis made for NLR. |
PMID:23814171 DOI:10.1177/1076029613494469 |
2015 Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis |
* The role of the nonspecific inflammatory markers in determining the anatomic extent of venous thromboembolism. |
- We aimed to investigate the relationship between the extent of venous thromboembolism (VTE) and nonspecific inflammatory markers such as neutrophil to lymphocyte ratio (NLR) and high-sensitivity C-reactive protein (hs-CRP). We retrospectively enrolled 77 patients with VTE (distal deep vein thrombosis [DVT], n = 19; proximal DVT, n = 32; and pulmonary thromboembolism [PTE], n = 26) and 34 healthy controls. In the performed analysis of variance, the levels of white blood cell, NLR, and hs-CRP were clearly different among the groups (control, distal and proximal DVT, and PTE) (P < .001). Especially, a significant increase from the control group to the DVT and PTE was observed in the analysis made for NLR. In the performed receiver-operating characteristic curve analysis, area under curve (AUC) = 0.849 and P < .001 were detected for NLR > 1.84. For this value, the sensitivity and specificity were determined as 88.2% and 67.6%, respectively. The NLR is an inexpensive and a readily available marker that may be effective in determining the extent of VTE, and it is useful for risk stratification in patients with VTE. |
(1)67 differences | (15)5 correlations | (29)3 influence | (44)2 dose-dependent |
(2)40 increase | (16)5 effects | (30)3 negative | (45)2 elevation |
(3)36 difference | (17)5 for | (31)3 number | (46)2 evidence |
(4)28 decrease | (18)5 increases | (32)3 roles | (47)2 factors |
(5)12 reduction | (19)5 risk | (33)2 (P | (48)2 group |
(6)11 predictors | (20)4 effect | (35)2 alterations | (49)2 inhibition |
(7)10 association | (21)4 in | (36)2 and | (50)2 interaction |
(8)9 improvement | (22)4 reductions | (37)2 at | (51)2 morbidity |
(9)8 *null* | (23)4 relationship | (38)2 between-group | (52)2 positive |
(10)7 changes | (24)3 (p | (39)2 blood | (53)2 prediction |
(11)7 predictor | (25)3 alteration | (40)2 challenge | (54)2 proportion |
(12)7 role | (26)3 as | (41)2 contribution | (55)2 source |
(13)6 correlation | (27)3 higher | (42)2 cytotoxic | (56)2 time |
(14)5 associations | (28)3 improvements | (43)2 decreases |
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