ELIZA

return kwic search for species out of >500 occurrences
321753 occurrences (No.65 in the rank) during 5 years in the PubMed. [cache]

207) Reactive oxygen species (ROS) are reported as a main factor for osteoblast cell death and further several bone diseases.

--- ABSTRACT ---

PMID:23788393 DOI:10.1177/0748233713491801

2015 Toxicology and industrial health

* Reactive oxygen species induce cell death via Akt signaling in rat osteoblast-like cell line ROS 17/2.8.

- In bones, osteoblasts are responsible for bone formation. The cell death of osteoblasts may cause a series of bone diseases and lead to bone loss, such as osteoarthrosis, hyperparathyroidism, and Paget's disease. Reactive oxygen species (ROS) are reported as a main factor for osteoblast cell death and further several bone diseases. However, the detailed mechanism is still largely unknown. Here, we found that ROS could induce cell death of rat osteoblast-like cell line ROS 17/2.8 via Akt (protein kinase B). Also, the mammalian target of rapamycin signaling was involved in this process. Our findings could help to reveal the cellular mechanism of osteoblast cell death, which is served for the pursuit of clinical treatment targets of relative bone diseases.

--- ABSTRACT END ---

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(1)93 null	(11)7 but	(21)3 can	(31)2 for
(2)46 of	(12)7 with	(22)3 could	(32)2 found
(3)34 in	(13)6 identification	(23)3 differences	(33)2 generated
(4)31 and	(14)5 determination	(24)3 have	(34)2 identification,
(5)19 (ROS)	(15)5 that	(25)3 level	(35)2 including
(6)18 were	(16)4 as	(26)3 may	(36)2 phytotoxicity
(7)12 is	(17)4 or	(27)2 (ROS),	(37)2 rather
(8)10 are	(18)4 to	(28)2 (overall	(38)2 such
(9)9 from	(19)4 which	(29)2 M
(10)9 was	(20)3 AEJ-89	(30)2 along

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--- WordNet output for species --- =>人類, 種, 種類 Overview of noun species The noun species has 2 senses (first 2 from tagged texts) 1. (27) species -- ((biology) taxonomic group whose members can interbreed) 2. (5) species -- (a specific kind of something; "a species of molecule"; "a species of villainy") Overview of noun specie The noun specie has 1 sense (no senses from tagged texts) 1. coinage, mintage, specie, metal money -- (coins collectively) --- WordNet end ---