ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for specific out of >500 occurrences
279736 occurrences (No.90 in the rank) during 5 years in the PubMed. [no cache] 500 found
1) Group differences were found only for decisions-to-drink, suggesting that they are specific to alcohol cues.
--- ABSTRACT ---
PMID:24373127 DOI:10.1111/adb.12121
2015 Addiction biology
* Neural mechanisms of high-risk decisions-to-drink in alcohol-dependent women.
- A hallmark of alcohol dependence (AD) is continually drinking despite the risk of negative consequences. Currently, it is not known if the pattern of disordered activation in AD is more compatible with an over-sensitive reward system, a deficit in control systems or a combination of both to produce the high risk-taking behavior observed in alcohol dependents (ADs). Here, alcohol cues were used in an ecological decisions-to-drink task that involved high- and low-risk scenarios where the chance of serious negative imagined consequences was varied. Non-alcohol cues were included as control stimuli. Functional magnetic resonance imaging (fMRI) was used to measure blood oxygen level-dependent (BOLD) signal change in 15 alcohol-dependent and 16 control women. This design allowed us to address two major questions concerning AD: first, is there a specific pattern of disordered activation that drives the heightened endorsement of high-risk decisions-to-drink in ADs? And, second, is that pattern specific to decisions-to-drink or does it generalize to other appetitive and/or neutral cues? The results showed that, during high-risk decisions-to-drink, alcohol-dependent women activated reward circuits, cognitive control circuits and regions of the default-mode network (DMN), while control women deactivated approach circuits and showed enhanced activation in regions of the DMN. Group differences were found only for decisions-to-drink, suggesting that they are specific to alcohol cues. Simultaneous activation of reward networks, cognitive control networks and the DMN in alcohol-dependent women suggests that over-endorsement of high-risk drinking decisions by alcohol-dependent women may be due to a problem with switching between different neural networks.
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(1)15 to (19)4 types (37)2 attention (55)2 lineages
(2)9 sequence (20)3 characteristics (38)2 barriers (56)2 measures
(3)7 and (21)3 features (39)2 computational (57)2 miRNAs
(4)7 cell (22)3 job (40)2 constitutive (58)2 molecular
(5)7 variations (23)3 target (41)2 criteria (59)2 neuronal
(6)6 cognitive (24)3 tendon (42)2 deficits (60)2 or
(7)6 genes (25)3 therapy (43)2 differences (61)2 parameters
(8)6 surface (26)3 type (44)2 divergence (62)2 phytotoxicity
(9)5 antibodies (27)3 variation (45)2 effect (63)2 polymerase
(10)5 for (28)2 *null* (46)2 elements (64)2 primers
(11)5 phobias (29)2 ECM (47)2 ethnocultural (65)2 protein
(12)4 brain (30)2 IgG (48)2 extracellular (66)2 proteins
(13)4 effects (31)2 PCR (49)2 fault (67)2 recommendations
(14)4 growth (32)2 age-dependent (50)2 function (68)2 requirements
(15)4 incidence (33)2 analysis (51)2 genetic (69)2 self-efficacy
(16)4 manner (34)2 antigen (52)2 genomic (70)2 targeted
(17)4 motor (35)2 antigens (53)2 information (71)2 tests
(18)4 needs (36)2 approach (54)2 inhibitors

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--- WordNet output for specific --- =>特有の, 特効薬, 明確な, 特定の, 種の, はっきりした Overview of noun specific The noun specific has 2 senses (no senses from tagged texts) 1. particular, specific -- (a fact about some part (as opposed to general); "he always reasons from the particular to the general") 2. specific -- (a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria") Overview of adj specific The adj specific has 4 senses (first 2 from tagged texts) 1. (39) specific -- ((sometimes followed by `to') applying to or characterized by or distinguishing something particular or special or unique; "rules with specific application"; "demands specific to the job"; "a specific and detailed account of the accident") 2. (5) specific -- (stated explicitly or in detail; "needed a specific amount") 3. specific -- (relating to or distinguishing or constituting a taxonomic species; "specific characters") 4. specific -- (being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements") --- WordNet end ---