ELIZA

return kwic search for studies out of >500 occurrences
532339 occurrences (No.23 in the rank) during 5 years in the PubMed. [cache]

94) The management of IBD in reproductive age and pregnant women remains still controversial, because literature data comes mostly from retrospective studies.

--- ABSTRACT ---

PMID:23749699 DOI:10.1007/s12282-013-0478-y

2015 Medycyna wieku rozwojowego

* [Influence of inflammatory bowel disease on pregnancy and fertility - optimal treatment and management].

- Inflammatory bowel diseases (IBD) affect mainly the young population and therefore fertility and pregnancy-related issues are important clinical considerations. Generally, men and women with IBD do not have decreased fertility compared to the general population. Drugs used for IBD do not affect significantly fertility in humans, except sulfasalazine, which causes a temporary reduction in spermatogenesis, but does not reduce fertility itself. The disease course during pregnancy and the risk of pregnancy-related complications depend mainly on the disease activity at the time of conception, therefore, pregnancy should be planned during a phase of remission. Except for methotrexate, mycophenolate mofetil and thalidomide, which are strongly contraindicated, drugs used for IBD appear safe in pregnancy, if they are administered carefully. The highest degree of safety was proved for 5-ASA- -containing agents, thiopurines and corticosteroids. The use of TNFα agents remains disputable, especially in the third trimester of pregnancy, due to their high concentration in the infant`s blood and the lack of data concerning its long-term safety. Surgery, if necessary, should be delayed if possible, although pregnancy is not a contraindication for surgical procedures. The management of IBD in reproductive age and pregnant women remains still controversial, because literature data comes mostly from retrospective studies. The aim of this paper was to summarize and to present proper management of patients with IBD prior to conception, as well as pregnant women and breast-feeding mothers with IBD, based on current European Crohn's and Colitis Organisation (ECCO) guidelines and available literature.

--- ABSTRACT END ---

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[frequency of next (right) word to studies]

(1)61 have	(14)8 with	(27)3 demonstrate	(40)2 including
(2)47 null	(15)7 should	(28)3 for	(41)2 indicated
(3)32 of	(16)6 is	(29)3 however,	(42)2 investigating
(4)26 are	(17)6 we	(30)3 performed	(43)2 involving
(5)26 on	(18)5 suggest	(31)3 reported	(44)2 it
(6)19 in	(19)5 the	(32)3 since	(45)2 or
(7)17 were	(20)4 as	(33)3 which	(46)2 provide
(8)16 and	(21)4 demonstrated	(34)2 about	(47)2 published
(9)15 to	(22)4 evaluating	(35)2 also	(48)2 regarding
(10)10 showed	(23)4 from	(36)2 can	(49)2 targeting
(11)8 revealed	(24)4 indicate	(37)2 concerning	(50)2 tested
(12)8 that	(25)4 show	(38)2 demonstrating	(51)2 used
(13)8 using	(26)3 based	(39)2 has	(52)2 was

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--- WordNet output for studies --- Overview of noun study The noun study has 10 senses (first 8 from tagged texts) 1. (90) survey, study -- (a detailed critical inspection) 2. (17) study, work -- (applying the mind to learning and understanding a subject (especially by reading); "mastering a second language requires a lot of work"; "no schools offer graduate study in interior design") 3. (6) report, study, written report -- (a written document describing the findings of some individual or group; "this accords with the recent study by Hill and Dale") 4. (6) study -- (a state of deep mental absorption; "she is in a deep study") 5. (6) study -- (a room used for reading and writing and studying; "he knocked lightly on the closed door of the study") 6. (3) discipline, subject, subject area, subject field, field, field of study, study, bailiwick -- (a branch of knowledge; "in what discipline is his doctorate?"; "teachers should be well trained in their subject"; "anthropology is the study of human beings") 7. (2) sketch, study -- (preliminary drawing for later elaboration; "he made several studies before starting to paint") 8. (1) cogitation, study -- (attentive consideration and meditation; "after much cogitation he rejected the offer") 9. study -- (someone who memorizes quickly and easily (as the lines for a part in a play); "he is a quick study") 10. study -- (a composition intended to develop one aspect of the performer's technique; "a study in spiccato bowing") Overview of verb study The verb study has 6 senses (first 6 from tagged texts) 1. (73) analyze, analyse, study, examine, canvass, canvas -- (consider in detail and subject to an analysis in order to discover essential features or meaning; "analyze a sonnet by Shakespeare"; "analyze the evidence in a criminal trial"; "analyze your real motives") 2. (17) study -- (be a student; follow a course of study; be enrolled at an institute of learning) 3. (15) study, consider -- (give careful consideration to; "consider the possibility of moving") 4. (13) learn, study, read, take -- (be a student of a certain subject; "She is reading for the bar exam") 5. (5) study, hit the books -- (learn by reading books; "He is studying geology in his room"; "I have an exam next week; I must hit the books now") 6. (2) study, meditate, contemplate -- (think intently and at length, as for spiritual purposes; "He is meditating in his study") --- WordNet end ---