ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for study out of >500 occurrences
1099112 occurrences (No.1 in the rank) during 5 years in the PubMed. [no cache] 500 found
14) The present study was carried out to understand the effect of TCDD on testicular steroidogenesis and sperm antioxidant system under the influence of increased level of corticosterone in the body.
--- ABSTRACT ---
PMID:23363575 DOI:10.1177/0748233713475501
2015 Toxicology and industrial health
* TCDD and corticosterone on testicular steroidogenesis and antioxidant system of epididymal sperm in rats.
- 2,3,7,8-Tetrachloro dibenzo-p-dioxin (TCDD), an endocrine-disrupting environmental pollutant, has been found to cause male reproductive toxicity. Glucocorticoids have been found to influence the metabolic pathway of TCDD. Stress, which affects the male reproductive function, is marked by an increase in the level and activity of glucocorticoids in the body. The present study was carried out to understand the effect of TCDD on testicular steroidogenesis and sperm antioxidant system under the influence of increased level of corticosterone in the body. Adult male rats were treated with either TCDD (100 ng/kg bw/ day) or corticosterone (3 mg/kg bw/day) or both for 15 days. Treatment with either TCDD or corticosterone was found to suppress the levels of steroidogenic acute regulatory protein and androgen-binding protein and reduce the activities of steroidogenic enzymes in testis while increasing oxidative stress in ventral prostate, seminal vesicles and epididymal sperm. In rats treated with both TCDD and corticosterone, the suppression of testicular steroidogenesis and increase in oxidative stress observed in ventral prostate, seminal vesicles and epididymal sperm were significant as compared to TCDD alone treated rats. The levels of Fas and FasL proteins were also increased in rats subjected to either TCDD or corticosterone treatment. In rats treated with both compounds, the increase observed in testicular levels of Fas and FasL was significant as compared to TCDD alone treated rats. Effect of TCDD on testicular steroidogenesis and antioxidant system of epididymal sperm may get enhanced under increased level of glucocorticoids in the body.
--- ABSTRACT END ---
[
right
kwic]
[frequency of next (right) word to study]
(1)109 was (16)6 used (31)2 1 (46)2 investigates
(2)36 we (17)5 included (32)2 and (47)2 it
(3)25 aimed (18)5 showed (33)2 as (48)2 objective
(4)24 *null* (19)5 subjects (34)2 assessed (49)2 participants
(5)15 the (20)4 a (35)2 compared (50)2 period
(6)14 investigated (21)4 also (36)2 data (51)2 provide
(7)14 is (22)4 demonstrates (37)2 demonstrated (52)2 provided
(8)13 examined (23)4 explored (38)2 determined (53)2 provides
(9)9 aims (24)4 found (39)2 evaluated (54)2 recommends
(10)9 were (25)4 on (40)2 evaluates (55)2 reveals
(11)8 of (26)3 examines (41)2 findings (56)2 suggest
(12)8 suggests (27)3 period, (42)2 has (57)2 three
(13)7 to (28)3 population (43)2 have
(14)6 in (29)3 revealed (44)2 highlighted
(15)6 may (30)3 shows (45)2 highlights

add keyword

--- WordNet output for study --- =>1.〜を勉強[研究]する, 学ぶ, 調べる, 2.調査, 勉強, 3.書斎, 勉強する Overview of noun study The noun study has 10 senses (first 8 from tagged texts) 1. (90) survey, study -- (a detailed critical inspection) 2. (17) study, work -- (applying the mind to learning and understanding a subject (especially by reading); "mastering a second language requires a lot of work"; "no schools offer graduate study in interior design") 3. (6) report, study, written report -- (a written document describing the findings of some individual or group; "this accords with the recent study by Hill and Dale") 4. (6) study -- (a state of deep mental absorption; "she is in a deep study") 5. (6) study -- (a room used for reading and writing and studying; "he knocked lightly on the closed door of the study") 6. (3) discipline, subject, subject area, subject field, field, field of study, study, bailiwick -- (a branch of knowledge; "in what discipline is his doctorate?"; "teachers should be well trained in their subject"; "anthropology is the study of human beings") 7. (2) sketch, study -- (preliminary drawing for later elaboration; "he made several studies before starting to paint") 8. (1) cogitation, study -- (attentive consideration and meditation; "after much cogitation he rejected the offer") 9. study -- (someone who memorizes quickly and easily (as the lines for a part in a play); "he is a quick study") 10. study -- (a composition intended to develop one aspect of the performer's technique; "a study in spiccato bowing") Overview of verb study The verb study has 6 senses (first 6 from tagged texts) 1. (73) analyze, analyse, study, examine, canvass, canvas -- (consider in detail and subject to an analysis in order to discover essential features or meaning; "analyze a sonnet by Shakespeare"; "analyze the evidence in a criminal trial"; "analyze your real motives") 2. (17) study -- (be a student; follow a course of study; be enrolled at an institute of learning) 3. (15) study, consider -- (give careful consideration to; "consider the possibility of moving") 4. (13) learn, study, read, take -- (be a student of a certain subject; "She is reading for the bar exam") 5. (5) study, hit the books -- (learn by reading books; "He is studying geology in his room"; "I have an exam next week; I must hit the books now") 6. (2) study, meditate, contemplate -- (think intently and at length, as for spiritual purposes; "He is meditating in his study") --- WordNet end ---