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1099112 occurrences (No.1 in the rank) during 5 years in the PubMed. [no cache] 500 found

402) The study period was 4 weeks.

--- ABSTRACT ---

PMID:22909270 DOI:10.1111/j.1740-8709.2012.00440.x

2015 Maternal & child nutrition

* Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial.

- Leg cramps are common in pregnant women. Currently, there is no standard treatment for pregnancy-induced leg cramps. The objective of this study was to evaluate the therapeutic efficacy of oral magnesium in pregnant women with leg cramps. This double-blinded, randomised, placebo-controlled trial included 86 healthy pregnant women, 14-34 weeks of gestation who had leg cramps at least twice per week. The study period was 4 weeks. Eighty women completed the study. Forty-one women were assigned to magnesium bisglycinate chelate (300 mg per day) and 39 women to placebo. Details of leg cramps were recorded before beginning the treatment and the fourth week of study. Outcome measure was the reduction of cramp frequency after treatment and cramp intensity measured by 100-mm visual analogue scale. Fifty per cent reduction of cramp frequency was significantly higher in the magnesium group than the placebo group (86.0% vs. 60.5%, P=0.007). The 50% reduction of cramp intensity was also significantly higher in the treatment group than in the placebo group (69.8% vs. 48.8%, P=0.048). There were no significant differences between the two groups in terms of side effects such as nausea and diarrhoea. These results demonstrated that oral magnesium supplement can improve the frequency and intensity of pregnancy-induced leg cramps. Therefore, oral magnesium may be a treatment option for women suffering from pregnancy-induced leg cramps.

--- ABSTRACT END ---

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(1)109 was	(16)6 used	(31)2 1	(46)2 investigates
(2)36 we	(17)5 included	(32)2 and	(47)2 it
(3)25 aimed	(18)5 showed	(33)2 as	(48)2 objective
(4)24 null	(19)5 subjects	(34)2 assessed	(49)2 participants
(5)15 the	(20)4 a	(35)2 compared	(50)2 period
(6)14 investigated	(21)4 also	(36)2 data	(51)2 provide
(7)14 is	(22)4 demonstrates	(37)2 demonstrated	(52)2 provided
(8)13 examined	(23)4 explored	(38)2 determined	(53)2 provides
(9)9 aims	(24)4 found	(39)2 evaluated	(54)2 recommends
(10)9 were	(25)4 on	(40)2 evaluates	(55)2 reveals
(11)8 of	(26)3 examines	(41)2 findings	(56)2 suggest
(12)8 suggests	(27)3 period,	(42)2 has	(57)2 three
(13)7 to	(28)3 population	(43)2 have
(14)6 in	(29)3 revealed	(44)2 highlighted
(15)6 may	(30)3 shows	(45)2 highlights

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--- WordNet output for study --- =>1.〜を勉強[研究]する, 学ぶ, 調べる, 2.調査, 勉強, 3.書斎, 勉強する Overview of noun study The noun study has 10 senses (first 8 from tagged texts) 1. (90) survey, study -- (a detailed critical inspection) 2. (17) study, work -- (applying the mind to learning and understanding a subject (especially by reading); "mastering a second language requires a lot of work"; "no schools offer graduate study in interior design") 3. (6) report, study, written report -- (a written document describing the findings of some individual or group; "this accords with the recent study by Hill and Dale") 4. (6) study -- (a state of deep mental absorption; "she is in a deep study") 5. (6) study -- (a room used for reading and writing and studying; "he knocked lightly on the closed door of the study") 6. (3) discipline, subject, subject area, subject field, field, field of study, study, bailiwick -- (a branch of knowledge; "in what discipline is his doctorate?"; "teachers should be well trained in their subject"; "anthropology is the study of human beings") 7. (2) sketch, study -- (preliminary drawing for later elaboration; "he made several studies before starting to paint") 8. (1) cogitation, study -- (attentive consideration and meditation; "after much cogitation he rejected the offer") 9. study -- (someone who memorizes quickly and easily (as the lines for a part in a play); "he is a quick study") 10. study -- (a composition intended to develop one aspect of the performer's technique; "a study in spiccato bowing") Overview of verb study The verb study has 6 senses (first 6 from tagged texts) 1. (73) analyze, analyse, study, examine, canvass, canvas -- (consider in detail and subject to an analysis in order to discover essential features or meaning; "analyze a sonnet by Shakespeare"; "analyze the evidence in a criminal trial"; "analyze your real motives") 2. (17) study -- (be a student; follow a course of study; be enrolled at an institute of learning) 3. (15) study, consider -- (give careful consideration to; "consider the possibility of moving") 4. (13) learn, study, read, take -- (be a student of a certain subject; "She is reading for the bar exam") 5. (5) study, hit the books -- (learn by reading books; "He is studying geology in his room"; "I have an exam next week; I must hit the books now") 6. (2) study, meditate, contemplate -- (think intently and at length, as for spiritual purposes; "He is meditating in his study") --- WordNet end ---