ELIZA

return kwic search for those out of >500 occurrences
303636 occurrences (No.74 in the rank) during 5 years in the PubMed. [no cache] 500 found

357) The results showed that while piglets developed effective cellular immune responses against CH-1a infection, those infected with HuN4 displayed ineffective cellular immunity, organ lesions and persistent elevated levels of immunoregulatory cytokines (IL-10 and TGF-β), which delayed the development of PRRSV-specific immune responses.

--- ABSTRACT ---

PMID:24308664 DOI:10.1111/tbed.12190

2015 Transboundary and emerging diseases

* Comparative Analysis of Immune Responses in Pigs to High and Low Pathogenic Porcine Reproductive and Respiratory Syndrome Viruses Isolated in China.

- The CH-1a and HuN4 strains of porcine reproductive and respiratory syndrome virus (PRRSV) show different pathogenicities in pigs. To understand host immune responses against these viruses, we investigated the dynamic changes in cytokine levels produced in peripheral blood of piglets infected with the highly pathogenic PRRSV HuN4 strain or the CH-1a strain. Clinical signs, virus loads and serum cytokine levels [interferon(IFN)-α, Interleukin (IL)-1, TNF-α, IL-6, IL-12, IFN-γ, IL-10 and TGF-β] were tested. The results showed that while piglets developed effective cellular immune responses against CH-1a infection, those infected with HuN4 displayed ineffective cellular immunity, organ lesions and persistent elevated levels of immunoregulatory cytokines (IL-10 and TGF-β), which delayed the development of PRRSV-specific immune responses. These results demonstrated that HuN4 infection induced higher cytokine levels than that of CH-1a infection induced. The changes in inflammatory cytokines intensified the inflammatory reaction and damaged the tissues and organs.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to those]

(1)94 of	(11)7 obtained	(21)3 seen	(31)2 on
(2)60 with	(12)4 aged	(22)3 whose	(32)2 parameters
(3)46 who	(13)4 at	(23)2 abilities	(33)2 prepared
(4)40 in	(14)4 individuals	(24)2 between	(34)2 published
(5)14 without	(15)4 related	(25)2 carrying	(35)2 regions
(6)12 that	(16)4 reported	(26)2 completing	(36)2 responsible
(7)9 found	(17)3 born	(27)2 experienced	(37)2 studies
(8)8 from	(18)3 not	(28)2 fed
(9)8 observed	(19)3 older	(29)2 infected
(10)7 living	(20)3 receiving	(30)2 involved

add keyword

--- WordNet output for those --- =>それらの --- WordNet end ---