ELIZA

return kwic search for through out of >500 occurrences
437431 occurrences (No.38 in the rank) during 5 years in the PubMed. [cache]

119) The International Society for Cell & Gene Therapy mesenchymal stromal cell (MSC) committee has been an interested observer of community interests in all matters related to MSC identity, mechanism of action, potency assessment and etymology, and it has regularly contributed to this conversation through a series of MSC pre-conferences and committee publications dealing with these matters.

--- ABSTRACT ---

PMID:33714704 DOI:10.1016/j.jcyt.2020.11.007

2021 Cytotherapy

* Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition.

- The International Society for Cell & Gene Therapy mesenchymal stromal cell (MSC) committee has been an interested observer of community interests in all matters related to MSC identity, mechanism of action, potency assessment and etymology, and it has regularly contributed to this conversation through a series of MSC pre-conferences and committee publications dealing with these matters. Arising from these reflections, the authors propose that an overlooked and potentially disruptive perspective is the impact of in vivo persistence on potency that is not predicted by surrogate cellular potency assays performed in vitro and how this translates to in vivo outcomes. Systemic delivery or extravascular implantation at sites removed from the affected organ system seems to be adequate in affecting clinical outcomes in many pre-clinical murine models of acute tissue injury and inflammatory pathology, including the recent European Medicines Agency-approved use of MSCs in Crohn-related fistular disease. The authors further propose that MSC viability and metabolic fitness likely dominate as a potency quality attribute, especially in recipients poised for salutary benefits as defined by emerging predictive biomarkers of response.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to through]

(1)82 the	(13)3 discussion	(25)2 Google	(37)2 improving
(2)42 a	(14)3 food	(26)2 MEDLINE,	(38)2 induction
(3)8 an	(15)3 information	(27)2 Medline,	(39)2 lipid
(4)8 this	(16)3 inhibition	(28)2 PubMed	(40)2 multiple
(5)7 which	(17)3 its	(29)2 PubMed,	(41)2 nutrition
(6)6 resolution	(18)3 modulation	(30)2 abutment	(42)2 providing
(7)4 October	(19)3 searches	(31)2 analysis	(43)2 reference
(8)4 different	(20)3 several	(32)2 assessment	(44)2 semi-structured
(9)4 various	(21)3 their	(33)2 binding	(45)2 simulation
(10)3 January	(22)3 these	(34)2 dual	(46)2 specific
(11)3 July	(23)2 April	(35)2 gap	(47)2 thematic
(12)3 both	(24)2 August	(36)2 genetic

add keyword

--- WordNet output for through --- =>直通の, のために, の間じゅう, 終わって, を貫いて, の中を通って, のいたるところに, を通じて Overview of adj through The adj through has 2 senses (first 1 from tagged texts) 1. (4) done, through, through with -- (having finished or arrived at completion; "certain to make history before he's done"; "it's a done deed"; "after the treatment, the patient is through except for follow-up"; "almost through with his studies") 2. through -- ((of a route or journey etc.) continuing without requiring stops or changes; "a through street"; "a through bus"; "through traffic") Overview of adv through The adv through has 5 senses (first 3 from tagged texts) 1. (5) through -- (from beginning to end; "read this book through") 2. (2) through -- (over the whole distance; "this bus goes through to New York") 3. (1) through -- (to completion; "think this through very carefully!") 4. through -- (in diameter; "this cylinder measures 15 inches through") 5. through, through and through -- (throughout the entire extent; "got soaked through in the rain"; "I'm frozen through"; "a letter shot through with the writer's personality"; "knew him through and through"; "boards rotten through and through") --- WordNet end ---