ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
return
kwic search for through out of >500 occurrences
437431 occurrences (No.38 in the rank) during 5 years in the PubMed. [no cache]
500 found
3) Our results show that ectopically expressed BRN2 adopts a nuclear localisation in all nuclei through the 4-cell stage of development, whereas only a subset of blastomeres in 8-cell stage embryos possess nuclear BRN2.
* Dynamic changes in nuclear import of a nuclear localisation signal-bearing substrate in 8-cell stage porcine embryos.
- Coordinated intracellular trafficking is critically important for proper timing of major cellular events during embryogenesis. Nuclear import mediated by the karyopherin α/β (importin α/β) heterodimer is perhaps the best characterised nuclear trafficking system in eukaryotic cells. Seven karyopherin α subtypes have been identified in the domestic pig, and although each karyopherin α subtype transports proteins bearing classical nuclear localisation signals (NLSs), individual karyopherin α subtypes have been shown to preferentially transport specific cargoes. The aim of the present study was to determine the mechanism by which BRN2, a transcription factor previously reported to be transported by the karyopherin α/β heterodimer, gains access to the nucleus in porcine oocytes and embryos. Using a combination of in vivo and in vitro assays, we tested the hypothesis that discrete karyopherin α subtypes transport BRN2 into the nuclei of porcine oocytes and cleavage stage embryos. Our results show that ectopically expressed BRN2 adopts a nuclear localisation in all nuclei through the 4-cell stage of development, whereas only a subset of blastomeres in 8-cell stage embryos possess nuclear BRN2. This pattern is unique to BRN2 because another ectopically expressed NLS-containing protein is able to adopt a nuclear localisation in all blastomeres of 8-cell stage embryos.
=>直通の, のために, の間じゅう, 終わって, を貫いて, の中を通って, のいたるところに, を通じて
Overview of adj through
The adj through has 2 senses (first 1 from tagged texts)
1. (4) done, through, through with -- (having finished or arrived at completion; "certain to make
history before he's done"; "it's a done deed"; "after the treatment, the patient is through except
for follow-up"; "almost through with his studies")
2. through -- ((of a route or journey etc.) continuing without requiring stops or changes; "a
through street"; "a through bus"; "through traffic")
Overview of adv through
The adv through has 5 senses (first 3 from tagged texts)
1. (5) through -- (from beginning to end; "read this book through")
2. (2) through -- (over the whole distance; "this bus goes through to New York")
3. (1) through -- (to completion; "think this through very carefully!")
4. through -- (in diameter; "this cylinder measures 15 inches through")
5. through, through and through -- (throughout the entire extent; "got soaked through in the rain";
"I'm frozen through"; "a letter shot through with the writer's personality"; "knew him through and
through"; "boards rotten through and through")
--- WordNet end ---