ELIZA

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296134 occurrences (No.80 in the rank) during 5 years in the PubMed. [no cache] 500 found

248) The patient was then treated with rituximab 375 mg/m(2) on days 1 and 8, and 100 mg total dose on days 15 and 22.

--- ABSTRACT ---

PMID:23634876 DOI:10.3109/09537104.2013.789842

2015 Platelets

* Successful use of rituximab in platelet transfusion refractoriness in a multi-transfused patient with myelodysplastic syndrome.

- A 61-year-old man with newly diagnosed INT-1 risk myelodysplastic syndrome--refractory cytopenia with multilineage dysplasia (MDS-RCMD) was not responsive to treatment, such as androgen, thalidomide, granulocyte--colony stimulating factor (G-CSF) combined with erythropoietin (EPO), interleukin-11 (IL-11) and thrombopoietin (TPO), and became transfusion dependent. Due to repeated blood transfusions, he developed platelet transfusion refractoriness (PTR) to platelets from cross-matched donors as well as random donors. Anti-HLA class I antibodies were positive with enzyme-linked immunosorbent assay; however, HLA-compatible platelet products were unavailable. PTR was unresponsive to high-dose immunoglobulin and plasma exchange. The patient was then treated with rituximab 375 mg/m(2) on days 1 and 8, and 100 mg total dose on days 15 and 22. Already after the first dose of rituximab, the patient was able to received successful platelet transfusion from all donors. Therefore rituximab may be considered as a potential therapy for PTR.

--- ABSTRACT END ---

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(1)187 of	(14)3 adhesive	(27)2 BGP	(40)2 organic
(2)21 length	(15)3 annual	(28)2 DNA,	(41)2 oxidant
(3)13 number	(16)3 delivered	(29)2 activity	(42)2 pleural
(4)7 antioxidant	(17)3 knee	(30)2 arch	(43)2 protein,
(5)7 protein	(18)3 length,	(31)2 biomass	(44)2 repetitions
(6)5 body	(19)3 optical	(32)2 collagen	(45)2 scores
(7)5 cholesterol	(20)3 or	(33)2 daily	(46)2 snack
(8)5 dose	(21)3 parenteral	(34)2 dietary	(47)2 soluble
(9)5 score	(22)3 polyphenols	(35)2 exercise	(48)2 stress
(10)4 HG	(23)3 population	(36)2 genome	(49)2 tumor
(11)4 amount	(24)3 sample	(37)2 health-care	(50)2 volume
(12)4 and	(25)3 suspended	(38)2 islet
(13)4 cell	(26)2 248	(39)2 mitochondrial

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--- WordNet output for total --- =>1.(車が)全壊する, 全損する, 2.全体の, 全ての, 総計の, 総体の, 全くの, 完全な, 総力の, 3.総額, 総計, 全体の, (車が)全壊する, 合計(する), なる Overview of noun total The noun total has 2 senses (first 2 from tagged texts) 1. (13) sum, total, totality, aggregate -- (the whole amount) 2. (6) sum, amount, total -- (a quantity obtained by the addition of a group of numbers) Overview of verb total The verb total has 3 senses (first 2 from tagged texts) 1. (16) total, number, add up, come, amount -- (add up in number or quantity; "The bills amounted to $2,000"; "The bill came to $2,000") 2. (2) total, tot, tot up, sum, sum up, summate, tote up, add, add together, tally, add up -- (determine the sum of; "Add all the people in this town to those of the neighboring town") 3. total -- (damage beyond the point of repair; "My son totaled our new car"; "the rock star totals his guitar at every concert") Overview of adj total The adj total has 2 senses (first 2 from tagged texts) 1. (31) entire, full, total -- (constituting the full quantity or extent; complete; "an entire town devastated by an earthquake"; "gave full attention"; "a total failure") 2. (2) full, total -- (complete in extent or degree and in every particular; "a full game"; "a total eclipse"; "a total disaster") --- WordNet end ---