ELIZA

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296134 occurrences (No.80 in the rank) during 5 years in the PubMed. [cache]

281) Articular chondrocytes and synovial cells were harvested during total knee arthroplasty.

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PMID:23165985 DOI:10.1002/term.1610

2015 Journal of tissue engineering and regenerative medicine

* Studies of the humoral factors produced by layered chondrocyte sheets.

- The authors aimed to repair and regenerate articular cartilage with layered chondrocyte sheets, produced using temperature-responsive culture dishes. The purpose of this study was to investigate the humoral factors produced by layered chondrocyte sheets. Articular chondrocytes and synovial cells were harvested during total knee arthroplasty. After co-culture, the samples were divided into three groups: a monolayer, 7 day culture sheet group (group M); a triple-layered, 7 day culture sheet group (group L); and a monolayer culture group with a cell count identical to that of group L (group C). The secretion of collagen type 1 (COL1), collagen type 2 (COL2), matrix metalloproteinase-13 (MMP13), transforming growth factor-β (TGFβ), melanoma inhibitory activity (MIA) and prostaglandin E2 (PGE2) were measured by enzyme-linked immunosorbent assay (ELISA). Layered chondrocyte sheets produced the most humoral factors. PGE2 expression declined over time in group C but was significantly higher in groups M and L. TGFβ expression was low in group C but was significantly higher in groups M and L (p<0.05). Our results suggest that the humoral factors produced by layered chondrocyte sheets may contribute to cartilaginous tissue repair and regeneration.

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(1)187 of	(14)3 adhesive	(27)2 BGP	(40)2 organic
(2)21 length	(15)3 annual	(28)2 DNA,	(41)2 oxidant
(3)13 number	(16)3 delivered	(29)2 activity	(42)2 pleural
(4)7 antioxidant	(17)3 knee	(30)2 arch	(43)2 protein,
(5)7 protein	(18)3 length,	(31)2 biomass	(44)2 repetitions
(6)5 body	(19)3 optical	(32)2 collagen	(45)2 scores
(7)5 cholesterol	(20)3 or	(33)2 daily	(46)2 snack
(8)5 dose	(21)3 parenteral	(34)2 dietary	(47)2 soluble
(9)5 score	(22)3 polyphenols	(35)2 exercise	(48)2 stress
(10)4 HG	(23)3 population	(36)2 genome	(49)2 tumor
(11)4 amount	(24)3 sample	(37)2 health-care	(50)2 volume
(12)4 and	(25)3 suspended	(38)2 islet
(13)4 cell	(26)2 248	(39)2 mitochondrial

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--- WordNet output for total --- =>1.(車が)全壊する, 全損する, 2.全体の, 全ての, 総計の, 総体の, 全くの, 完全な, 総力の, 3.総額, 総計, 全体の, (車が)全壊する, 合計(する), なる Overview of noun total The noun total has 2 senses (first 2 from tagged texts) 1. (13) sum, total, totality, aggregate -- (the whole amount) 2. (6) sum, amount, total -- (a quantity obtained by the addition of a group of numbers) Overview of verb total The verb total has 3 senses (first 2 from tagged texts) 1. (16) total, number, add up, come, amount -- (add up in number or quantity; "The bills amounted to $2,000"; "The bill came to $2,000") 2. (2) total, tot, tot up, sum, sum up, summate, tote up, add, add together, tally, add up -- (determine the sum of; "Add all the people in this town to those of the neighboring town") 3. total -- (damage beyond the point of repair; "My son totaled our new car"; "the rock star totals his guitar at every concert") Overview of adj total The adj total has 2 senses (first 2 from tagged texts) 1. (31) entire, full, total -- (constituting the full quantity or extent; complete; "an entire town devastated by an earthquake"; "gave full attention"; "a total failure") 2. (2) full, total -- (complete in extent or degree and in every particular; "a full game"; "a total eclipse"; "a total disaster") --- WordNet end ---